Literature DB >> 21102573

Do gastrointestinal transit times and colonic dimensions change with time since spinal cord injury?

P M Faaborg1, P Christensen, M Rosenkilde, S Laurberg, K Krogh.   

Abstract

STUDY
DESIGN: Long-term follow-up study.
OBJECTIVES: To determine whether gastrointestinal transit times (GITTs) and colonic dimensions change during the first or subsequent decades after spinal cord injury (SCI).
SETTING: Aarhus University Hospital, Denmark.
METHODS: GITT and colonic dimensions were evaluated by means of radio-opaque markers. Group A (n=12) was investigated 1 year after SCI and again 13 (range 11-14) years later. Group B (n=10) was studied 19 (range 9-36) years after injury and again 12 (range 11-12) years later. All had been treated with conservative bowel management.
RESULTS: In group A, the median GITT 1 year after injury was 4.3 (range 1.1-6.5) days and 13 years later, it was 3.2 (range 1.3-6.5) days, P=0.96. In group B, the median GITT 19 year after injury was 3.4 (range 0.6-5.9) days and 12 years later, it was 3.2 (range 1.9-5.5) days, P=0.77. None of the two groups experienced a significant change in the diameter of the caecum/ascending colon, transverse colon, descending colon or the sigmoid during long-term follow-up. Megacolon was present in four patients at baseline and in five at follow-up.
CONCLUSION: GITTs and colonic dimensions did not change, neither during the first decade nor long after SCI.

Entities:  

Mesh:

Year:  2010        PMID: 21102573     DOI: 10.1038/sc.2010.162

Source DB:  PubMed          Journal:  Spinal Cord        ISSN: 1362-4393            Impact factor:   2.772


  4 in total

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2.  Megacolon as an atypical presentation of cervical myelopathy.

Authors:  Jacob Y L Oh; Kevin J H Kwek; Seh-Wee Tee; Mark Tan
Journal:  J Spine Surg       Date:  2017-03

Review 3.  Neural pathways for colorectal control, relevance to spinal cord injury and treatment: a narrative review.

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Journal:  Spinal Cord       Date:  2017-11-16       Impact factor: 2.772

Review 4.  The Potential Role of Inflammation in Modulating Endogenous Hippocampal Neurogenesis After Spinal Cord Injury.

Authors:  Arthur Sefiani; Cédric G Geoffroy
Journal:  Front Neurosci       Date:  2021-06-18       Impact factor: 4.677

  4 in total

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