| Literature DB >> 21102436 |
Adam G Hendricks, Jacob E Lazarus, Erika L F Holzbaur.
Abstract
Cytoplasmic dynein drives vesicular transport from the periphery to the cell body of neurons. Missense mutations in the dynein tail domain cause neurodegenerative disease in mouse models. new data on the effect of one such dynein mutation provide insight into the intramolecular communication and flexible stepping of this essential cellular motor.Entities:
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Year: 2010 PMID: 21102436 DOI: 10.1038/ncb1210-1126
Source DB: PubMed Journal: Nat Cell Biol ISSN: 1465-7392 Impact factor: 28.824