Literature DB >> 21098900

Current surgical management of severe peyronie's disease.

Sava V Perovic1, Rados P Djinovic.   

Abstract

OBJECTIVES: To report the principles of penile resculpturing of different deformities caused by M. Peyronie: restoration of penile length, girth and shape with or without penile prosthesis implantation.
METHODS: In the period between February 2007 and March 2009, we performed grafting surgery for M. Peyronie in 98 patients aged between 24 and 72 years (mean 52 years). Penile deformities were diferent: dorsal curvature in 54 (55%), lateral in 7 (7%), ventral in 11 (11%), and combined curvature in 21 (21%) associated corporal narrowing was present in 24 patients (24%). Four (4%) patients presented isolated penile shortening without other deformity. Isolated diffuse corporal narrowing without shortening was found in two (2%) patients. Severity of curvature ranges from 60 to 90 degrees, mean 72. Thirty one (31%) patients had associated ED. Surgical options for severe Peyronie's disease were: single grafting in 26 pts (26%), complex grafting including circular tunical incision in 36 pts (36%), and in patients with ED the same procedures combined with penile prosthesis implantation (37 pts, 38%). Surgical correction was based on measurement of the tunical defect and precise calculation of graft size and shape. Penile straightening and lengthening was achieved by equalizing of shortened penile side/s with the longest one (convex) and grafting. Penile width is reestablished with additional longitudinal incision/s and grafting; graft width is determined by measurement of difference in circumference between normal and narrowed part of the corpora. We used Intexen LP (AMS) as a grafting material in all cases.
RESULTS: The mean follow-up was 15 months (6-25). Mean penile length gain without prosthesis was 2.8cm (1.5-4.2) and with prosthesis 3.2cm (2-4.5cm). Insuficient straightening was in 5 patients (>15 degree) where Neuro Vascular Bundle (NVB) was limiting factor. Twenty four patients reported hypoesthesia and reduced orgasmic sensitivity that recovered spontaneously after 3-6 months. De-novo ED occurred in 6 pts and progression of disease in 6 patients. Infection occurred only in one patient with penile prosthesis implantation. Overall patients' satisfaction was 95%.
CONCLUSIONS: Complete tunical reconstruction in IPP can be performed as a safe procedure by transversal, longitudinal and circular grafting with or without simultaneous penile prosthesis implantation. Maximum penile length, girth and shape restoration can be achieved using geometrical calculation, regardless of type of deformity.

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Year:  2010        PMID: 21098900

Source DB:  PubMed          Journal:  Arch Esp Urol        ISSN: 0004-0614            Impact factor:   0.436


  3 in total

1.  Update on plication procedures for Peyronie's disease and other penile deformities.

Authors:  Elizabeth M Mobley; Molly E Fuchs; Jeremy B Myers; William O Brant
Journal:  Ther Adv Urol       Date:  2012-12

Review 2.  Use of grafting materials during penile prosthesis implantation in patients with Peyronie's disease-a systematic review.

Authors:  Francesco Chierigo; Carlo Bettocchi; Felix Campos-Juanatey; Fabio Castiglione; Luis A Kluth; Carlo Terrone; Asif Muneer
Journal:  Int J Impot Res       Date:  2021-10-30       Impact factor: 2.408

Review 3.  A comprehensive narrative review of residual curvature correction during penile prosthesis implantation in patients with severe erectile dysfunction and concomitant Peyronie's disease.

Authors:  Ioannis Sokolakis; Nikolaos Pyrgidis; Ioannis Mykoniatis; Fotios Dimitriadis; Georgios Hatzichristodoulou
Journal:  Transl Androl Urol       Date:  2021-06
  3 in total

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