Development of a multimodal monitoring platform for medical research.

A low cost multimodal monitoring and signal processing platform is presented. A modular and flexible system was developed, aimed to continuous acquisition of several biological variables at patient bed-head and further processing with application specific algorithms. System hardware is made of a six-channel isolation and signal conditioning front-end along with a high resolution analog-to-digital converter board connected to a standard laptop. Whole system hardware is compact and light weight, which ensures portability and ease of use at intensive care units. System software is divided in three modules: Acquisition, Signal Processing and Patients Data Management. The first one allows configuring each acquisition channel parameters, depending on the biological variable connected to it, and to store up to several hours of continuous data. Signal processing module implements novel algorithms for research purposes like dynamic cerebral autoregulation, optimal perfusion pressure, critical closing pressure or pulsatility index. It is flexible enough to easily add new processing algorithms, export data to different formats and create graphical reports. Patients data management module organizes acquired records, which allows selecting cases for new studies based on different criteria like monitored variables or pathological information. In this work, whole system architecture is described and algorithms included into the cerebral hemodynamics toolbox are presented along with experimental results.