| Literature DB >> 2109703 |
H Denz1, D Fuchs, H Huber, D Nachbaur, G Reibnegger, J Thaler, E R Werner, H Wachter.
Abstract
In this study, we further investigated a possible link between activation of cell-mediated immunity and anaemia in patients with haematological neoplasias. We compared serum concentrations of interferon-gamma and neopterin with haemoglobin levels. Significantly increased interferon-gamma and neopterin concentrations indicated persistent activation of cell-mediated immunity. Neopterin levels correlated significantly to interferon-gamma concentrations and inversely to haemoglobin levels. The data indicate an association between activated macrophages and the development of anaemia in patients with haematological neoplasias.Entities:
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Year: 1990 PMID： 2109703 DOI： 10.1111/j.1600-0609.1990.tb00374.x
Source DB: PubMed Journal: Eur J Haematol ISSN： 0902-4441 Impact factor: 2.997