Literature DB >> 21096558

Development of a microbicide-releasing diaphragm as an HIV prevention strategy.

Ian Major1, Deborah Lowry, Karl Malcolm, David Woolfson, Jessica Cohen, Paul Labarre, Maggie Kilbourne-Brook, Gene Saxon, David Friend.   

Abstract

Contraceptive diaphragms offer a discreet method of pregnancy protection that women can use when needed with no side effects. Incorporating antiretroviral HIV microbicides into such devices may also provide protection against HIV infection. The paper gives a brief outline of the work being conducted by PATH, CONRAD and QUB on the development of a microbicide-releasing SILCS diaphragm. The design, engineering and manufacturing challenges that have been encountered will be discussed, as well as the potential impact such a device could have in the developing world.

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Year:  2010        PMID: 21096558     DOI: 10.1109/IEMBS.2010.5627333

Source DB:  PubMed          Journal:  Annu Int Conf IEEE Eng Med Biol Soc        ISSN: 2375-7477


  3 in total

1.  Assessing the potential of the Woman's Condom for vaginal drug delivery.

Authors:  Lindsay F Kramzer; Jessica Cohen; Jesse Schubert; Charlene S Dezzutti; Bernard J Moncla; David Friend; Lisa C Rohan
Journal:  Contraception       Date:  2015-05-19       Impact factor: 3.375

2.  Drug-eluting fibers for HIV-1 inhibition and contraception.

Authors:  Cameron Ball; Emily Krogstad; Thanyanan Chaowanachan; Kim A Woodrow
Journal:  PLoS One       Date:  2012-11-28       Impact factor: 3.240

3.  Vaginal rings for delivery of HIV microbicides.

Authors:  R Karl Malcolm; Susan M Fetherston; Clare F McCoy; Peter Boyd; Ian Major
Journal:  Int J Womens Health       Date:  2012-11-20
  3 in total

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