Application of multivariate empirical mode decomposition for seizure detection in EEG signals.

We present a method for the analysis of electroencephalogram (EEG) signals which has the potential to distinguish between ictal and seizure-free intracranial EEG recordings. This is achieved by analyzing common frequency components in multichannel EEG recordings, using the multivariate empirical mode decomposition (MEMD) algorithm. The mean frequency of the signal is calculated by applying the Hilbert-Huang transform on the resulting intrinsic mode functions (IMFs). It has been shown that the mean frequency estimates for the ictal and seizure-free EEG recordings are statistically different, and hence, can serve as a test statistic to distinguish between the two classes of signals. Simulation results on real world EEG signals support the analysis and demonstrate the potential of the proposed scheme.