Literature DB >> 21095187

Investigation of some medicinal plants traditionally used for treatment of malaria in Kenya as potential sources of antimalarial drugs.

C N Muthaura1, J M Keriko, S Derese, A Yenesew, G M Rukunga.   

Abstract

Malaria is a major public health problem in many tropical and subtropical countries and the burden of this disease is getting worse, mainly due to the increasing resistance of Plasmodium falciparum against the widely available antimalarial drugs. There is an urgent need for discovery of new antimalarial agents. Herbal medicines for the treatment of various diseases including malaria are an important part of the cultural diversity and traditions of which Kenya's biodiversity has been an integral part. Two major antimalarial drugs widely used today came originally from indigenous medical systems, that is quinine and artemisinin, from Peruvian and Chinese ancestral treatments, respectively. Thus ethnopharmacology is a very important resource in which new therapies may be discovered. The present review is an analysis of ethnopharmacological publications on antimalarial therapies from some Kenyan medicinal plants.
Copyright © 2010 Elsevier Inc. All rights reserved.

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Year:  2010        PMID: 21095187     DOI: 10.1016/j.exppara.2010.11.004

Source DB:  PubMed          Journal:  Exp Parasitol        ISSN: 0014-4894            Impact factor:   2.011


  6 in total

1.  Ethnodiagnostic skills of the digo community for malaria: a lead to traditional bioprospecting.

Authors:  Joseph Mwanzia Nguta; James M Mbaria; Peter K Gathumbi; Daniel Gakuya; John David Kabasa; Stephen Gitahi Kiama
Journal:  Front Pharmacol       Date:  2011-06-24       Impact factor: 5.810

2.  Antimalarial activity of plumbagin in vitro and in animal models.

Authors:  Wiriyaporn Sumsakul; Tullayakorn Plengsuriyakarn; Wanna Chaijaroenkul; Vithoon Viyanant; Juntra Karbwang; Kesara Na-Bangchang
Journal:  BMC Complement Altern Med       Date:  2014-01-12       Impact factor: 3.659

3.  Antiplasmodial potential and quantification of aloin and aloe-emodin in Aloe vera collected from different climatic regions of India.

Authors:  Sandeep Kumar; Manila Yadav; Amita Yadav; Pooja Rohilla; Jaya Parkash Yadav
Journal:  BMC Complement Altern Med       Date:  2017-07-17       Impact factor: 3.659

Review 4.  Important Flavonoids and Their Role as a Therapeutic Agent.

Authors:  Asad Ullah; Sidra Munir; Syed Lal Badshah; Noreen Khan; Lubna Ghani; Benjamin Gabriel Poulson; Abdul-Hamid Emwas; Mariusz Jaremko
Journal:  Molecules       Date:  2020-11-11       Impact factor: 4.411

5.  Antiprotozoal dimeric naphthylisoquinolines, mbandakamines B3 and B4, and related 5,8'-coupled monomeric alkaloids, ikelacongolines A-D, from a Congolese Ancistrocladus liana.

Authors:  Jean-Pierre Mufusama; Doris Feineis; Virima Mudogo; Marcel Kaiser; Reto Brun; Gerhard Bringmann
Journal:  RSC Adv       Date:  2019-04-16       Impact factor: 4.036

6.  Nanoincorporation of Plumbagin in Micelles Increase Its in Vivo Anti-Plasmodial Properties.

Authors:  Hamid Rashidzadeh; Payam Zamani; Mahdi Amiri; Seyed Mehdi Hassanzadeh; Ali Ramazani
Journal:  Iran J Parasitol       Date:  2022 Apr-Jun       Impact factor: 1.217

  6 in total

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