Literature DB >> 21094459

Licensing PPARγ to work in macrophages.

Claudio J Villanueva1, Peter Tontonoz.   

Abstract

The mechanisms that direct cell-type-specific peroxisome proliferator-activated receptor (PPAR) gene programs are poorly understood. In this issue of Immunity, Szanto et al. (2010) identify signal transducer and activator of transcription 6 as a transcriptional switch that licenses PPARγ-dependent gene expression in macrophages and dendritic cells.
Copyright © 2010 Elsevier Inc. All rights reserved.

Entities:  

Year:  2010        PMID： 21094459      PMCID： PMC3005613          DOI： 10.1016/j.immuni.2010.11.017

Source DB:  PubMed          Journal:  Immunity        ISSN： 1074-7613            Impact factor:   31.745


  8 in total

1.  Cell-specific determinants of peroxisome proliferator-activated receptor gamma function in adipocytes and macrophages.

Authors:  Martina I Lefterova; David J Steger; David Zhuo; Mohammed Qatanani; Shannon E Mullican; Geetu Tuteja; Elisabetta Manduchi; Gregory R Grant; Mitchell A Lazar
Journal:  Mol Cell Biol       Date:  2010-02-22       Impact factor: 4.272

2.  Interleukin-4-dependent production of PPAR-gamma ligands in macrophages by 12/15-lipoxygenase.

Authors:  J T Huang; J S Welch; M Ricote; C J Binder; T M Willson; C Kelly; J L Witztum; C D Funk; D Conrad; C K Glass
Journal:  Nature       Date:  1999-07-22       Impact factor: 49.962

3.  mPPAR gamma 2: tissue-specific regulator of an adipocyte enhancer.

Authors:  P Tontonoz; E Hu; R A Graves; A I Budavari; B M Spiegelman
Journal:  Genes Dev       Date:  1994-05-15       Impact factor: 11.361

4.  Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance.

Authors:  Justin I Odegaard; Roberto R Ricardo-Gonzalez; Matthew H Goforth; Christine R Morel; Vidya Subramanian; Lata Mukundan; Alex Red Eagle; Divya Vats; Frank Brombacher; Anthony W Ferrante; Ajay Chawla
Journal:  Nature       Date:  2007-05-21       Impact factor: 49.962

5.  Arginase I induction by modified lipoproteins in macrophages: a peroxisome proliferator-activated receptor-gamma/delta-mediated effect that links lipid metabolism and immunity.

Authors:  Alejandro Gallardo-Soler; Carlos Gómez-Nieto; María Luisa Campo; Chaitra Marathe; Peter Tontonoz; Antonio Castrillo; Inés Corraliza
Journal:  Mol Endocrinol       Date:  2008-03-06

6.  STAT6 transcription factor is a facilitator of the nuclear receptor PPARγ-regulated gene expression in macrophages and dendritic cells.

Authors:  Attila Szanto; Balint L Balint; Zsuzsanna S Nagy; Endre Barta; Balazs Dezso; Attila Pap; Lajos Szeles; Szilard Poliska; Melinda Oros; Ronald M Evans; Yaacov Barak; John Schwabe; Laszlo Nagy
Journal:  Immunity       Date:  2010-11-24       Impact factor: 31.745

7.  PPAR-delta senses and orchestrates clearance of apoptotic cells to promote tolerance.

Authors:  Lata Mukundan; Justin I Odegaard; Christine R Morel; Jose E Heredia; Julia W Mwangi; Roberto R Ricardo-Gonzalez; Y P Sharon Goh; Alex Red Eagle; Shannon E Dunn; Jennifer U H Awakuni; Khoa D Nguyen; Lawrence Steinman; Sara A Michie; Ajay Chawla
Journal:  Nat Med       Date:  2009-10-18       Impact factor: 87.241

8.  Preserved glucose tolerance in high-fat-fed C57BL/6 mice transplanted with PPARgamma-/-, PPARdelta-/-, PPARgammadelta-/-, or LXRalphabeta-/- bone marrow.

Authors:  Chaitra Marathe; Michelle N Bradley; Cynthia Hong; Lily Chao; Damien Wilpitz; Jon Salazar; Peter Tontonoz
Journal:  J Lipid Res       Date:  2008-09-04       Impact factor: 5.922
  8 in total
  5 in total

1.  Pioglitazone, PPARγ agonist, attenuates experimental autoimmune neuritis.

Authors:  Hhoonisha Ramkalawan; Yu-Zhong Wang; Ameet Hurbungs; Yan-Fang Yang; Fa-Fa Tian; Wen-Bin Zhou; Jing Li; Huan Yang; Bo Xiao; Wei Zhang
Journal:  Inflammation       Date:  2012-08       Impact factor: 4.092

Review 2.  Role of peroxisome proliferator-activated receptors in non-alcoholic fatty liver disease inflammation.

Authors:  Amanda Karolina Soares Silva; Christina Alves Peixoto
Journal:  Cell Mol Life Sci       Date:  2018-05-22       Impact factor: 9.261

3.  Effect of modulation of PPAR-γ activity on Kupffer cells M1/M2 polarization in the development of non-alcoholic fatty liver disease.

Authors:  Wenjing Luo; Qinyu Xu; Qi Wang; Huimin Wu; Jing Hua
Journal:  Sci Rep       Date:  2017-03-16       Impact factor: 4.379

4.  N-Propargyl caffeate amide (PACA) prevents cardiac fibrosis in experimental myocardial infarction by promoting pro-resolving macrophage polarization.

Authors:  Yuanyuan Cheng; Dan Luo; Yingke Zhao; Jianhui Rong
Journal:  Aging (Albany NY)       Date:  2020-03-23       Impact factor: 5.682

5.  Rosiglitazone Suppresses Renal Crystal Deposition by Ameliorating Tubular Injury Resulted from Oxidative Stress and Inflammatory Response via Promoting the Nrf2/HO-1 Pathway and Shifting Macrophage Polarization.

Authors:  Hongyan Lu; Xifeng Sun; Min Jia; Fa Sun; Jianguo Zhu; Xiaolong Chen; Kun Chen; Kehua Jiang
Journal:  Oxid Med Cell Longev       Date:  2021-10-14       Impact factor: 6.543
  5 in total

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