Jessica M Dixon1, Robin L Carver. 1. Department of Infection Prevention, WakeMed Health & Hospitals, 3000 New Bern Ave., Raleigh, NC 27610, USA. jedixon@wakemed.org
Abstract
BACKGROUND: Central line-associated bloodstream infections (CLABSI) contribute to increased morbidity, mortality, length of stay, and excessive cost of care. METHODS: This study was an observational cohort study using historical controls in the setting of a 9-bed surgical intensive care unit in a Level I trauma center; all patients admitted or transferred into the unit were enrolled in the study. OBJECTIVES: A quality improvement intervention protocol was instituted to reduce CLABSI incidence with a 3-month effectiveness study using 2% chlorhexidine gluconate-impregnated cloths for daily patient bathing; education of surgical intensive care unit staff on changes to CLABSI prevention protocol and all existing CLABSI prevention policies and bundles already in place; and compliance monitoring and documentation. RESULTS: The 3-month effectiveness study showed a decrease in CLABSI rates from 12.07 CLABSIs per 1000 central line-days to 3.17 CLABSIs per 1000 central line-days (73.7% rate reduction; P = .0358). CONCLUSION: CLABSI incidence rates were reduced in a high-risk patient population using evidence-based prevention bundles and implementing daily bathing with 2% chlorhexidine gluconate nonrinse cloths.
BACKGROUND: Central line-associated bloodstream infections (CLABSI) contribute to increased morbidity, mortality, length of stay, and excessive cost of care. METHODS: This study was an observational cohort study using historical controls in the setting of a 9-bed surgical intensive care unit in a Level I trauma center; all patients admitted or transferred into the unit were enrolled in the study. OBJECTIVES: A quality improvement intervention protocol was instituted to reduce CLABSI incidence with a 3-month effectiveness study using 2% chlorhexidine gluconate-impregnated cloths for daily patient bathing; education of surgical intensive care unit staff on changes to CLABSI prevention protocol and all existing CLABSI prevention policies and bundles already in place; and compliance monitoring and documentation. RESULTS: The 3-month effectiveness study showed a decrease in CLABSI rates from 12.07 CLABSIs per 1000 central line-days to 3.17 CLABSIs per 1000 central line-days (73.7% rate reduction; P = .0358). CONCLUSION: CLABSI incidence rates were reduced in a high-risk patient population using evidence-based prevention bundles and implementing daily bathing with 2% chlorhexidine gluconate nonrinse cloths.
Authors: Vinay K Giri; Kristin G Kegerreis; Yi Ren; Lauren M Bohannon; Erica Lobaugh-Jin; Julia A Messina; Anita Matthews; Yvonne M Mowery; Elizabeth Sito; Martha Lassiter; Jennifer L Saullo; Sin-Ho Jung; Li Ma; Morris Greenberg; Tessa M Andermann; Marcel R M van den Brink; Jonathan U Peled; Antonio L C Gomes; Taewoong Choi; Cristina J Gasparetto; Mitchell E Horwitz; Gwynn D Long; Richard D Lopez; David A Rizzieri; Stefanie Sarantopoulos; Nelson J Chao; Deborah H Allen; Anthony D Sung Journal: Transplant Cell Ther Date: 2021-01-07
Authors: Melvin Chugh Makhni; Kolawole Jegede; Joseph Lombardi; Susan Whittier; Prakash Gorroochurn; Ronald A Lehman; K Daniel Riew Journal: J Am Acad Orthop Surg Date: 2018-01-15 Impact factor: 3.020