Literature DB >> 21093218

Heart rate dynamics in temporal lobe epilepsy-A long-term follow-up study.

Eija Suorsa1, Juha T Korpelainen, Hanna Ansakorpi, Heikki V Huikuri, Ville Suorsa, Vilho V Myllylä, Jouko I T Isojärvi.   

Abstract

The aim of the present study was to prospectively evaluate long-term changes in interictal heart rate variability (HRV) in patients with temporal lobe epilepsy (TLE). A 24-h ECG was recorded at baseline and after a mean follow-up of 6.1 years in 18 patients with refractory TLE and 18 patients with well-controlled TLE. After the follow-up, the Poincaré components SD(1) (p=0.039) and SD(2) (p=0.001) were decreased in patients with refractory TLE compared to baseline, whereas in patients with well-controlled TLE no changes (p>0.05) in HR variability were observed. The reduction in HRV seems to be progressive in patients with chronic refractory TLE with recurrent seizures. 2010 Elsevier B.V. All rights reserved.

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Year:  2010        PMID： 21093218     DOI： 10.1016/j.eplepsyres.2010.10.005

Source DB:  PubMed          Journal:  Epilepsy Res        ISSN： 0920-1211            Impact factor:   3.045


  9 in total

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