Literature DB >> 21093

Reversible graft versus host reaction as cause of erythrophagic splenomegaly in a child?

J D Beck, J E Weinig, H K Müller-Hermelink, E M Lemmel.   

Abstract

The case history of a 9 months old infant with hepatosplenomegaly, pancytopnaenia and disturbances of clotting and cellular immune reactivity is reported. The spleen was removed and showed striking erythrophagocytosis by proliferating histiocytes, typical of "familial erythrophagocytic reticulosis" (Farquhar). A graft-versus-host reaction is discussed as a possible underlying cause. The favourable clinical course and full recovery point to an interrelation with primary hypersplenism.

Entities:  

Mesh：

Year:  1977        PMID： 21093     DOI： 10.1007/BF00442199

Source DB:  PubMed          Journal:  Eur J Pediatr        ISSN： 0340-6199            Impact factor:   3.183


  33 in total

1.  Familial haemophagocytic reticulosis.

Authors:  J W FARQUHAR; A E CLAIREAUX
Journal:  Arch Dis Child       Date:  1952-12       Impact factor: 3.791

2.  Thymic dysplasia ("Swiss agammaglobulinemia"). I. Graft versus host reaction following bone-marrow transfusion.

Authors:  M E Miller
Journal:  J Pediatr       Date:  1967-05       Impact factor: 4.406

3.  "Histiocytosis".

Authors:  S P Gotoff; N B Esterly
Journal:  J Pediatr       Date:  1974-10       Impact factor: 4.406

4.  Hypofibrinogenemia and thrombocytopenia in familial hemophagocytic reticulosis.

Authors:  P D McClure; P Strachan; E F Saunders
Journal:  J Pediatr       Date:  1974-07       Impact factor: 4.406

5.  [The modern theory of hypersplenism on the basis of cytokinetic findings].

Authors:  W Pöttgen
Journal:  Dtsch Med Wochenschr       Date:  1972-07-21       Impact factor: 0.628

6.  Familial haemophagocytic reticulosis in first cousins.

Authors:  N R Buist; R N Jones; T R Cavens
Journal:  Arch Dis Child       Date:  1971-10       Impact factor: 3.791

7.  Familial haemophagocytic reticulosis.

Authors:  R J Bell; A J Brafield; N D Barnes; N E France
Journal:  Arch Dis Child       Date:  1968-10       Impact factor: 3.791

8.  Graft-versus-host disease. Liver involvement in splenectomized rats.

Authors:  S Levine
Journal:  Transplantation       Date:  1968-03       Impact factor: 4.939

9.  The graft versus host reaction in man after bone marrow transplantation: pathology, pathogenesis, clinical features, and implication.

Authors:  R E Slavin; G W Santos
Journal:  Clin Immunol Immunopathol       Date:  1973-07

10.  Congenital hemophagocytic reticulosis.

Authors:  A Koto; R Morecki; M Santorineou
Journal:  Am J Clin Pathol       Date:  1976-04       Impact factor: 2.493
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  2 in total

1.  Familial haemophagocytic lymphohistiocytosis in two brothers: possible relationship between impaired immune function and clinical picture of graft-versus-host disease.

Authors:  N Rascio; M Duse; G L Marseglia; L Nespoli; A G Ugazio
Journal:  Eur J Pediatr       Date:  1984-09       Impact factor: 3.183

Review 2.  Familial hemophagocytic lymphohistiocytosis.

Authors:  G E Janka
Journal:  Eur J Pediatr       Date:  1983 Jun-Jul       Impact factor: 3.183
  2 in total

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