Literature DB >> 21091784

Minimal erythema dose and minimal melanogenesis dose relate better to objectively measured skin type than to Fitzpatricks skin type.

Hans Christian Wulf1, Peter A Philipsen, Mette H Ravnbak.   

Abstract

BACKGROUND: Fitzpatrick skin type (FST I-IV) is a subjective expression of ultraviolet (UV) sensitivity based on erythema and tanning reactivity after a single exposure. Pigment protection factor (PPF) is an objective measurement of skin sensitivity in all skin types after a single exposure.
METHODS: The aim was to compare FST and PPF with clinically determined minimal erythema dose (MED) and minimal melanogenesis dose (MMD) in 84 persons with skin types I-V both after single and multiple exposures (one, four, five, six, or 12) to buttock and back skin.
RESULTS: FST was better correlated to MED than to MMD, and FST correlated better to constitutive than to facultative pigmented areas after multiple exposures rather than to a single exposure. PPF was generally much better correlated to MED and MMD than FST especially after a single exposure and multiple exposures with steady-state pigmentation. Multiple regression analyses showed that MED was the only significant, or most important determinator, of both FST and PPF. The correlation coefficient was highly significant for PPF (r² =82).
CONCLUSIONS: PPF is a better predictor of the individual UV sensitivity (linear relation) than FST (only 4 grades) and PPF can substitute FST.
© 2010 John Wiley & Sons A/S.

Entities:  

Mesh:

Year:  2010        PMID: 21091784     DOI: 10.1111/j.1600-0781.2010.00544.x

Source DB:  PubMed          Journal:  Photodermatol Photoimmunol Photomed        ISSN: 0905-4383            Impact factor:   3.135


  5 in total

1.  Evidence for a new paradigm for ultraviolet exposure: a universal schedule that is skin phototype independent.

Authors:  Sharon A Miller; Sergio G Coelho; Scott W Miller; Yuji Yamaguchi; Vincent J Hearing; Janusz Z Beer
Journal:  Photodermatol Photoimmunol Photomed       Date:  2012-08       Impact factor: 3.135

2.  Non-invasive diffuse reflectance measurements of cutaneous melanin content can predict human sensitivity to ultraviolet radiation.

Authors:  Sergio G Coelho; Barbara Z Zmudzka; Lanlan Yin; Sharon A Miller; Yuji Yamaguchi; Taketsugu Tadokoro; Vincent J Hearing; Janusz Z Beer
Journal:  Exp Dermatol       Date:  2013-04       Impact factor: 3.960

3.  Pigmentary Markers in Danes--Associations with Quantitative Skin Colour, Nevi Count, Familial Atypical Multiple-Mole, and Melanoma Syndrome.

Authors:  Peter Johansen; Jeppe Dyrberg Andersen; Linnea Nørgård Madsen; Henrik Ullum; Martin Glud; Claus Børsting; Robert Gniadecki; Niels Morling
Journal:  PLoS One       Date:  2016-03-03       Impact factor: 3.240

Review 4.  The impact of skin colour on human photobiological responses.

Authors:  Damilola Fajuyigbe; Antony R Young
Journal:  Pigment Cell Melanoma Res       Date:  2016-08-16       Impact factor: 4.693

5.  Concomitant DNA methylation and transcriptome signatures define epidermal responses to acute solar UV radiation.

Authors:  Nicholas Holzscheck; Jörn Söhle; Torsten Schläger; Cassandra Falckenhayn; Elke Grönniger; Ludger Kolbe; Horst Wenck; Lara Terstegen; Lars Kaderali; Marc Winnefeld; Katharina Gorges
Journal:  Sci Rep       Date:  2020-07-31       Impact factor: 4.379

  5 in total

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