Cutaneous spindle cell squamous cell carcinoma in nevus sebaceous.

A case of a 28 year-old Chinese male who presented with a rapidly growing tumor within a nevus sebaceous on his right cheek. The tumor was excised and immunohistochemical analysis and histology were consistent with spindle-cell squamous cell carcinoma. To the best of our knowledge, it is the first report of cutaneous spindle-cell squamous cell carcinoma developing in nevus sebaceous in the English literature. This report highlights the importance of early excision of any nevus sebaceous with a history of change.