Literature DB >> 21091291

Natural regulatory T cells in autoimmunity.

Elaine V Lourenço1, Antonio La Cava.   

Abstract

The suppressive/immunomodulatory function of CD4(+)CD25(+)FOXP3(+) regulatory T (Treg) cells is crucial for the maintenance of immune homeostasis, which helps to prevent autoimmunity and reduce the inflammation induced by pathogens and environmental insults. This review summarizes the current knowledge on the types and mechanisms of action of Treg cells and their role in the immune tolerance to self-antigens, with a particular focus on naturally occurring Treg cells.

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Year:  2010        PMID： 21091291      PMCID： PMC3057884          DOI： 10.3109/08916931003782155

Source DB:  PubMed          Journal:  Autoimmunity        ISSN： 0891-6934            Impact factor:   2.815


  137 in total

1.  CD28 costimulation of developing thymocytes induces Foxp3 expression and regulatory T cell differentiation independently of interleukin 2.

Authors:  Xuguang Tai; Michelle Cowan; Lionel Feigenbaum; Alfred Singer
Journal:  Nat Immunol       Date:  2005-01-09       Impact factor: 25.606

2.  From vanilla to 28 flavors: multiple varieties of T regulatory cells.

Authors:  Ethan M Shevach
Journal:  Immunity       Date:  2006-08       Impact factor: 31.745

3.  CD4+CD25high regulatory cells in human peripheral blood.

Authors:  C Baecher-Allan; J A Brown; G J Freeman; D A Hafler
Journal:  J Immunol       Date:  2001-08-01       Impact factor: 5.422

4.  Isolation and functional characterization of regulatory CD25brightCD4+ T cells from the target organ of patients with rheumatoid arthritis.

Authors:  Duojia Cao; Vivianne Malmström; Clare Baecher-Allan; David Hafler; Lars Klareskog; Christina Trollmo
Journal:  Eur J Immunol       Date:  2003-01       Impact factor: 5.532

5.  Granzyme B and perforin are important for regulatory T cell-mediated suppression of tumor clearance.

Authors:  Xuefang Cao; Sheng F Cai; Todd A Fehniger; Jiling Song; Lynne I Collins; David R Piwnica-Worms; Timothy J Ley
Journal:  Immunity       Date:  2007-10-04       Impact factor: 31.745

6.  CD4+CD25bright regulatory T cells actively regulate inflammation in the joints of patients with the remitting form of juvenile idiopathic arthritis.

Authors:  Ismé M de Kleer; Lucy R Wedderburn; Leonie S Taams; Alka Patel; Hemlata Varsani; Mark Klein; Wilco de Jager; Gisela Pugayung; Francesca Giannoni; Ger Rijkers; Salvatore Albani; Wietse Kuis; Berent Prakken
Journal:  J Immunol       Date:  2004-05-15       Impact factor: 5.422

7.  Single cell analysis shows decreasing FoxP3 and TGFbeta1 coexpressing CD4+CD25+ regulatory T cells during autoimmune diabetes.

Authors:  Shannon M Pop; Carmen P Wong; Donna A Culton; Stephen H Clarke; Roland Tisch
Journal:  J Exp Med       Date:  2005-04-18       Impact factor: 14.307

8.  Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3.

Authors:  WanJun Chen; Wenwen Jin; Neil Hardegen; Ke-Jian Lei; Li Li; Nancy Marinos; George McGrady; Sharon M Wahl
Journal:  J Exp Med       Date:  2003-12-15       Impact factor: 14.307

9.  CD25+ CD4+ T cells, expanded with dendritic cells presenting a single autoantigenic peptide, suppress autoimmune diabetes.

Authors:  Kristin V Tarbell; Sayuri Yamazaki; Kara Olson; Priscilla Toy; Ralph M Steinman
Journal:  J Exp Med       Date:  2004-06-07       Impact factor: 14.307

10.  Cyclic adenosine monophosphate is a key component of regulatory T cell-mediated suppression.

Authors:  Tobias Bopp; Christian Becker; Matthias Klein; Stefan Klein-Hessling; Alois Palmetshofer; Edgar Serfling; Valeska Heib; Marc Becker; Jan Kubach; Steffen Schmitt; Sabine Stoll; Hansjörg Schild; Martin S Staege; Michael Stassen; Helmut Jonuleit; Edgar Schmitt
Journal:  J Exp Med       Date:  2007-05-14       Impact factor: 14.307
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  28 in total

1.  APL-1, an altered peptide ligand derived from heat-shock protein, alone or combined with methotrexate attenuates murine collagen-induced arthritis.

Authors:  Norailys Lorenzo; Fiorella Altruda; Lorenzo Silengo; Maria Del Carmen Dominguez
Journal:  Clin Exp Med       Date:  2016-05-09       Impact factor: 3.984

Review 2.  Male gender bias in autism and pediatric autoimmunity.

Authors:  Kevin G Becker
Journal:  Autism Res       Date:  2012-03-17       Impact factor: 5.216

3.  Lys63-polyubiquitination by the E3 ligase casitas B-lineage lymphoma-b (Cbl-b) modulates peripheral regulatory T cell tolerance in patients with systemic lupus erythematosus.

Authors:  J Romo-Tena; S Rajme-López; L Aparicio-Vera; J Alcocer-Varela; D Gómez-Martín
Journal:  Clin Exp Immunol       Date:  2017-10-19       Impact factor: 4.330

Review 4.  Regulatory T Cells in SLE: Biology and Use in Treatment.

Authors:  Sophia Giang; Antonio La Cava
Journal:  Curr Rheumatol Rep       Date:  2016-11       Impact factor: 4.592

Review 5.  Functional Defects of Treg Cells: New Targets in Rheumatic Diseases, Including Ankylosing Spondylitis.

Authors:  Jinlin Miao; Ping Zhu
Journal:  Curr Rheumatol Rep       Date:  2018-04-16       Impact factor: 4.592

Review 6.  Immunomodulation of autoimmune arthritis by pro-inflammatory cytokines.

Authors:  Eugene Y Kim; Kamal D Moudgil
Journal:  Cytokine       Date:  2017-04-25       Impact factor: 3.861

Review 7.  Breaking tolerance to thyroid antigens: changing concepts in thyroid autoimmunity.

Authors:  Sandra M McLachlan; Basil Rapoport
Journal:  Endocr Rev       Date:  2013-12-04       Impact factor: 19.871

8.  High viral burden restricts short-lived effector cell number at late times postinfection through increased natural regulatory T cell expansion.

Authors:  Samuel Amoah; Beth C Holbrook; Rama D Yammani; Martha A Alexander-Miller
Journal:  J Immunol       Date:  2013-04-15       Impact factor: 5.422

9.  The Presence and Preferential Activation of Regulatory T Cells Diminish Adoptive Transfer of Autoimmune Diabetes by Polyclonal Nonobese Diabetic (NOD) T Cell Effectors into NSG versus NOD-scid Mice.

Authors:  Maximiliano Presa; Yi-Guang Chen; Alexandra E Grier; Edward H Leiter; Michael A Brehm; Dale L Greiner; Leonard D Shultz; David V Serreze
Journal:  J Immunol       Date:  2015-08-17       Impact factor: 5.422

Review 10.  FoxP3 Expression in Macrophages, Cancer, and B Cells-Is It Real?

Authors:  Zahava Vadasz; Elias Toubi
Journal:  Clin Rev Allergy Immunol       Date:  2017-06       Impact factor: 8.667
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