Literature DB >> 21090801

Cytotoxic triterpenoids from Maytenus retusa.

Sandra M Oramas-Royo1, Haydee Chávez, Patricia Martín-Rodíguez, Leandro Fernández-Pérez, Angel G Ravelo, Ana Estévez-Braun.   

Abstract

Seven new triterpenoids (1-7) and 36 known compounds were isolated from the root bark of Maytenus retusa. Their structures were determined by 1D and 2D spectroscopic studies. Several compounds were evaluated for their cytotoxicity against the human tumor cell lines HL-60 and MCF-7. Some of them were cytotoxic, with IC(50) values ranging between 0.2 and 4.7 μM.

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Year:  2010        PMID： 21090801     DOI： 10.1021/np100517u

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  4 in total

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Authors:  George R Pettit; Noeleen Melody; Frank Hempenstall; Jean-Charles Chapuis; Thomas L Groy; Lee Williams
Journal:  J Nat Prod       Date:  2014-04-02       Impact factor: 4.050
  4 in total

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