Literature DB >> 21090784

Three-dimensional structures of OSW-1 and its congener.

Kaori Sakurai1, Takuro Fukumoto, Keiichi Noguchi, Noriyuki Sato, Hiroki Asaka, Naomi Moriyama, Masafumi Yohda.   

Abstract

The 3D structures of an antitumor glycosylsterol OSW-1 and its closely related congener were investigated by NMR studies and an X-ray crystallographic analysis. The disaccharide moiety was found as a structural scaffold for the formation of a hydrophobic cluster by the biologically required functionalities.

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Year:  2010        PMID: 21090784     DOI: 10.1021/ol1025519

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  2 in total

1.  New insights into structure-activity relationship of ipomoeassin F from its bioisosteric 5-oxa/aza analogues.

Authors:  Guanghui Zong; Xianwei Sun; Rima Bhakta; Lucas Whisenhunt; Zhijian Hu; Feng Wang; Wei Q Shi
Journal:  Eur J Med Chem       Date:  2017-12-12       Impact factor: 6.514

2.  Galtonosides A-E: Antiproliferative and Antiplasmodial Cholestane Glycosides from Galtonia regalis.

Authors:  Yongle Du; Brooke A Martin; Ana Lisa Valenciano; Jason A Clement; Michael Goetz; Maria B Cassera; David G I Kingston
Journal:  J Nat Prod       Date:  2020-03-31       Impact factor: 4.050

  2 in total

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