Literature DB >> 21089759

Dose modeling in ultraviolet phototherapy.

David Robert Grimes1, Chris Robbins, Neil John O'Hare.   

Abstract

PURPOSE: Ultraviolet phototherapy is widely used in the treatment of numerous skin conditions. This treatment is well established and largely beneficial to patients on both physical and psychological levels; however, overexposure to ultraviolet radiation (UVR) can have detrimental effects, such as erythemal responses and ocular damage in addition to the potentially carcinogenic nature of UVR. For these reasons, it is essential to control and quantify the radiation dose incident upon the patient to ensure that it is both biologically effective and has the minimal possible impact on the surrounding unaffected tissue.
METHODS: To date, there has been little work on dose modeling, and the output of artificial UVR sources is an area where research has been recommended. This work characterizes these sources by formalizing an approach from first principles and experimentally examining this model.
RESULTS: An implementation of a line source model is found to give impressive accuracy and quantifies the output radiation well.
CONCLUSIONS: This method could potentially serve as a basis for a full computational dose model for quantifying patient dose.

Entities:  

Mesh:

Year:  2010        PMID: 21089759     DOI: 10.1118/1.3484093

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  3 in total

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Authors:  Ana L Tomás; Anna Reichel; Patrícia M Silva; Pedro G Silva; João Pinto; Inês Calado; Joana Campos; Ilídio Silva; Vasco Machado; Roberto Laranjeira; Paulo Abreu; Paulo Mendes; Nabiha Ben Sedrine; Nuno C Santos
Journal:  J Photochem Photobiol B       Date:  2022-07-23       Impact factor: 6.814

2.  Estimating oxygen distribution from vasculature in three-dimensional tumour tissue.

Authors:  David Robert Grimes; Pavitra Kannan; Daniel R Warren; Bostjan Markelc; Russell Bates; Ruth Muschel; Mike Partridge
Journal:  J R Soc Interface       Date:  2016-03       Impact factor: 4.118

3.  UVC Germicidal Units: Determination of Dose Received and Parameters to be Considered for N95 Respirator Decontamination and Reuse.

Authors:  Indermeet Kohli; Alexis B Lyons; Bob Golding; Shanthi Narla; Angeli E Torres; Angela Parks-Miller; David Ozog; Henry W Lim; Iltefat H Hamzavi
Journal:  Photochem Photobiol       Date:  2020-09-07       Impact factor: 3.521

  3 in total

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