Literature DB >> 21089754

Monte Carlo characterization of skin doses in 6 MV transverse field MRI-linac systems: effect of field size, surface orientation, magnetic field strength, and exit bolus.

B M Oborn1, P E Metcalfe, M J Butson, A B Rosenfeld.   

Abstract

PURPOSE: The main focus of this work is to continue investigations into the Monte Carlo predicted skin doses seen in MRI-guided radiotherapy. In particular, the authors aim to characterize the 70 microm skin doses over a larger range of magnetic field strength and x-ray field size than in the current literature. The effect of surface orientation on both the entry and exit sides is also studied. Finally, the use of exit bolus is also investigated for minimizing the negative effects of the electron return effect (ERE) on the exit skin dose.
METHODS: High resolution GEANT4 Monte Carlo simulations of a water phantom exposed to a 6 MV x-ray beam (Varian 2100C) have been performed. Transverse magnetic fields of strengths between 0 and 3 T have been applied to a 30 x 30 x 20 cm3 phantom. This phantom is also altered to have variable entry and exit surfaces with respect to the beam central axis and they range from -75 degrees to +75 degrees. The exit bolus simulated is a 1 cm thick (water equivalent) slab located on the beam exit side.
RESULTS: On the entry side, significant skin doses at the beam central axis are reported for large positive surface angles and strong magnetic fields. However, over the entry surface angle range of -30 degrees to -60 degrees, the entry skin dose is comparable to or less than the zero magnetic field skin dose, regardless of magnetic field strength and field size. On the exit side, moderate to high central axis skin dose increases are expected except at large positive surface angles. For exit bolus of 1 cm thickness, the central axis exit skin dose becomes an almost consistent value regardless of magnetic field strength or exit surface angle. This is due to the almost complete absorption of the ERE electrons by the bolus.
CONCLUSIONS: There is an ideal entry angle range of -30 degrees to -60 degrees where entry skin dose is comparable to or less than the zero magnetic field skin dose. Other than this, the entry skin dose increases are significant, especially at higher magnetic fields. On the exit side there is mostly moderate to high skin dose increases for 0.2-3 T with the only exception being large positive angles. Exit bolus of 1 cm thickness will have a significant impact on lowering such exit skin dose increases that occur as a result of the ERE.

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Year:  2010        PMID: 21089754     DOI: 10.1118/1.3488980

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  10 in total

1.  Monte Carlo simulations of patient dose perturbations in rotational-type radiotherapy due to a transverse magnetic field: a tomotherapy investigation.

Authors:  Y M Yang; M Geurts; J B Smilowitz; E Sterpin; B P Bednarz
Journal:  Med Phys       Date:  2015-02       Impact factor: 4.071

2.  Feasibility of normal tissue dose reduction in radiotherapy using low strength magnetic field.

Authors:  Nuri Hyun Jung; Youngseob Shin; In-Hye Jung; Jungwon Kwak
Journal:  Radiat Oncol J       Date:  2015-09-30

3.  Emergence of MR-Linac in Radiation Oncology: Successes and Challenges of Riding on the MRgRT Bandwagon.

Authors:  Indra J Das; Poonam Yadav; Bharat B Mittal
Journal:  J Clin Med       Date:  2022-08-31       Impact factor: 4.964

Review 4.  Advances in Image-Guided Radiotherapy in the Treatment of Oral Cavity Cancer.

Authors:  Hsin-Hua Nien; Li-Ying Wang; Li-Jen Liao; Ping-Yi Lin; Chia-Yun Wu; Pei-Wei Shueng; Chen-Shuan Chung; Wu-Chia Lo; Shih-Chiang Lin; Chen-Hsi Hsieh
Journal:  Cancers (Basel)       Date:  2022-09-23       Impact factor: 6.575

Review 5.  The potential for an enhanced role for MRI in radiation-therapy treatment planning.

Authors:  P Metcalfe; G P Liney; L Holloway; A Walker; M Barton; G P Delaney; S Vinod; W Tome
Journal:  Technol Cancer Res Treat       Date:  2013-04-24

Review 6.  Optimizing MR-Guided Radiotherapy for Breast Cancer Patients.

Authors:  Maureen L Groot Koerkamp; Jeanine E Vasmel; Nicola S Russell; Simona F Shaitelman; Carmel N Anandadas; Adam Currey; Danny Vesprini; Brian M Keller; Chiara De-Colle; Kathy Han; Lior Z Braunstein; Faisal Mahmood; Ebbe L Lorenzen; Marielle E P Philippens; Helena M Verkooijen; Jan J W Lagendijk; Antonetta C Houweling; H J G Desiree van den Bongard; Anna M Kirby
Journal:  Front Oncol       Date:  2020-07-28       Impact factor: 6.244

Review 7.  Medical physics challenges in clinical MR-guided radiotherapy.

Authors:  Christopher Kurz; Giulia Buizza; Guillaume Landry; Florian Kamp; Moritz Rabe; Chiara Paganelli; Guido Baroni; Michael Reiner; Paul J Keall; Cornelis A T van den Berg; Marco Riboldi
Journal:  Radiat Oncol       Date:  2020-05-05       Impact factor: 3.481

8.  Monte Carlo simulations of out-of-field skin dose due to spiralling contaminant electrons in a perpendicular magnetic field.

Authors:  Victor N Malkov; Sara L Hackett; Bram van Asselen; Bas W Raaymakers; Jochem W H Wolthaus
Journal:  Med Phys       Date:  2019-02-14       Impact factor: 4.071

9.  Calibration of the EBT3 Gafchromic Film Using HNN Deep Learning.

Authors:  Liyun Chang; Shyh-An Yeh; Sheng-Yow Ho; Hueisch-Jy Ding; Pang-Yu Chen; Tsair-Fwu Lee
Journal:  Biomed Res Int       Date:  2021-01-31       Impact factor: 3.411

10.  Characterizing magnetically focused contamination electrons by off-axis irradiation on an inline MRI-Linac.

Authors:  Elizabeth Patterson; Bradley M Oborn; Dean Cutajar; Urszula Jelen; Gary Liney; Anatoly B Rosenfeld; Peter E Metcalfe
Journal:  J Appl Clin Med Phys       Date:  2022-03-25       Impact factor: 2.243

  10 in total

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