Literature DB >> 21088648

Acellular dermal matrix for the treatment and prevention of implant-associated breast deformities.

Scott L Spear1, Mitchel Seruya, Mark W Clemens, Steven Teitelbaum, Maurice Y Nahabedian.   

Abstract

BACKGROUND: Acellular dermal matrix has been increasingly accepted in prosthetic breast reconstruction. Observed benefits include improved control and support of implant position, better implant coverage, and the suggestion of a decreased capsular contracture rate. Based on this positive experience, it is not surprising that acellular dermal matrix would be applied to other challenging implant-related problems. This study investigates the use of acellular dermal matrix for correction or prevention of implant-associated breast deformities.
METHODS: Patients who underwent primary aesthetic breast surgery or secondary aesthetic or reconstructive breast surgery using acellular dermal matrix and implants between November of 2003 and October of 2009 were reviewed retrospectively. Patient demographics, indications for acellular dermal matrix, and acellular dermal matrix type and inset pattern were identified. Preoperative and postoperative photographs, success or failure of the procedure, complications, and need for related or unrelated revision surgery were recorded.
RESULTS: Fifty-two patients had acellular dermal matrix placed alongside 77 breast prostheses, with a mean follow-up of 8.6 months (range, 0.4 to 30.4 months). Indications included prevention of implant bottoming-out (n = 6), treatment of malposition (n = 32), rippling (n = 20), capsular contracture (n = 16), and skin flap deficiency (n = 16). Seventy-four breasts (96.1 percent) were managed successfully with acellular dermal matrix. Three failures consisted of one breast with bottoming-out following treatment of capsular contracture, one breast with major infection requiring device explantation, and one breast with recurrent rippling. There was a 9.1 percent total complication rate, consisting of three mild infections, one major infection necessitating explantation, one hematoma, and one seroma.
CONCLUSION: Based on this experience in 77 breasts, acellular dermal matrix has shown promise in treating and preventing capsular contracture, rippling, implant malposition, and soft-tissue thinning.

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Year:  2011        PMID: 21088648     DOI: 10.1097/PRS.0b013e31820436af

Source DB:  PubMed          Journal:  Plast Reconstr Surg        ISSN: 0032-1052            Impact factor:   4.730


  30 in total

1.  Acellular dermal matrices: Use in reconstructive and aesthetic breast surgery.

Authors:  Sheina A Macadam; Peter A Lennox
Journal:  Can J Plast Surg       Date:  2012

Review 2.  Current strategies with 2-staged prosthetic breast reconstruction.

Authors:  Christin Harless; Steven R Jacobson
Journal:  Gland Surg       Date:  2015-06

3.  Capsular contracture in implant based breast reconstruction-the effect of porcine acellular dermal matrix.

Authors:  Alessia M Lardi; Mark Ho-Asjoe; Klaus Junge; Jian Farhadi
Journal:  Gland Surg       Date:  2017-02

4.  Pro-Fibrotic CD26-Positive Fibroblasts Are Present in Greater Abundance in Breast Capsule Tissue of Irradiated Breasts.

Authors:  Mimi R Borrelli; Dre Irizzary; Ronak A Patel; Dung Nguyen; Arash Momeni; Michael T Longaker; Derrick C Wan
Journal:  Aesthet Surg J       Date:  2020-03-23       Impact factor: 4.283

Review 5.  Alloplastic adjuncts in breast reconstruction.

Authors:  Miguel S Cabalag; Marie Rostek; George S Miller; Michael P Chae; Tam Quinn; Warren M Rozen; David J Hunter-Smith
Journal:  Gland Surg       Date:  2016-04

6.  Xenogeneic acellular dermal matrix in combination with pectoralis major myocutaneous flap reconstructs hypopharynx and cervical esophagus.

Authors:  Danhui Yin; Qinglai Tang; Shuang Wang; Shisheng Li; Xiangbo He; Jiajia Liu; Bingbing Liu; Mi Yang; Xinming Yang
Journal:  Eur Arch Otorhinolaryngol       Date:  2014-10-31       Impact factor: 2.503

7.  Placement of a non-cross-linked porcine-derived acellular dermal matrix during preperitoneal laparoscopic inguinal hernia repair.

Authors:  Giath Alshkaki
Journal:  Int Surg       Date:  2013 Apr-Jun

8.  Robotic-assisted latissimus dorsi harvest in delayed-immediate breast reconstruction.

Authors:  Mark W Clemens; Steven Kronowitz; Jesse C Selber
Journal:  Semin Plast Surg       Date:  2014-02       Impact factor: 2.314

9.  Prevention of implant malposition in inframammary augmentation mammaplasty.

Authors:  Yoon Ji Kim; Yang Woo Kim; Young Woo Cheon
Journal:  Arch Plast Surg       Date:  2014-07-15

10.  Early multicentre experience of pre-pectoral implant based immediate breast reconstruction using Braxon®.

Authors:  Sadaf Jafferbhoy; Mihir Chandarana; Maria Houlihan; Rishikesh Parmeshwar; Sankaran Narayanan; Soni Soumian; Simon Harries; Lucie Jones; Dayalan Clarke
Journal:  Gland Surg       Date:  2017-12
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