Literature DB >> 21088605

Sex differences: implications for the obesity-asthma association.

Akshay Sood1.   

Abstract

We have demonstrated in several studies that obesity and adipokines are more strongly associated with asthma in women than in men. The reason for this controversial sex difference is not known. Based on our previous studies, we hypothesize that sex-related differences in ectopic fat may explain the obesity-asthma association in women.

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Year:  2011        PMID： 21088605      PMCID： PMC3019137          DOI： 10.1097/JES.0b013e318201f0c4

Source DB:  PubMed          Journal:  Exerc Sport Sci Rev        ISSN： 0091-6331            Impact factor:   6.230


  40 in total

1.  Adiponectin attenuates allergen-induced airway inflammation and hyperresponsiveness in mice.

Authors:  Stephanie A Shore; Raya D Terry; Lesley Flynt; Aimin Xu; Christopher Hug
Journal:  J Allergy Clin Immunol       Date:  2006-05-30       Impact factor: 10.793

2.  Prospective study of body mass index, weight change, and risk of adult-onset asthma in women.

Authors:  C A Camargo; S T Weiss; S Zhang; W C Willett; F E Speizer
Journal:  Arch Intern Med       Date:  1999-11-22

3.  Adiposity, asthma, and airway inflammation.

Authors:  Christene R McLachlan; Richie Poulton; George Car; Jan Cowan; Susan Filsell; Justina M Greene; D Robin Taylor; David Welch; Avis Williamson; Malcolm R Sears; Robert J Hancox
Journal:  J Allergy Clin Immunol       Date:  2006-12-04       Impact factor: 10.793

4.  The association between obesity and asthma is stronger in nonallergic than allergic adults.

Authors:  Yue Chen; Robert Dales; Ying Jiang
Journal:  Chest       Date:  2006-09       Impact factor: 9.410

5.  Effect of leptin on allergic airway responses in mice.

Authors:  Stephanie A Shore; Igor N Schwartzman; Matthew S Mellema; Lesley Flynt; Amy Imrich; Richard A Johnston
Journal:  J Allergy Clin Immunol       Date:  2005-01       Impact factor: 10.793

6.  Central obesity is associated with nonatopic but not atopic asthma in a representative population sample.

Authors:  Sarah L Appleton; Robert J Adams; David H Wilson; Anne W Taylor; Richard E Ruffin
Journal:  J Allergy Clin Immunol       Date:  2006-11-07       Impact factor: 10.793

7.  Asthma severity is associated with body mass index and early menarche in women.

Authors:  Raphaëlle Varraso; Valérie Siroux; Jean Maccario; Isabelle Pin; Francine Kauffmann
Journal:  Am J Respir Crit Care Med       Date:  2004-11-19       Impact factor: 21.405

8.  Overweight, obesity, and incident asthma: a meta-analysis of prospective epidemiologic studies.

Authors:  David A Beuther; E Rand Sutherland
Journal:  Am J Respir Crit Care Med       Date:  2007-01-18       Impact factor: 21.405

9.  Gender differences of regional abdominal fat distribution and their relationships with insulin sensitivity in healthy and glucose-intolerant Thais.

Authors:  Chatchalit Rattarasarn; Rattana Leelawattana; Supamai Soonthornpun; Worawong Setasuban; Atchara Thamprasit
Journal:  J Clin Endocrinol Metab       Date:  2004-12       Impact factor: 5.958

10.  Association between leptin and asthma in adults.

Authors:  A Sood; E S Ford; C A Camargo
Journal:  Thorax       Date:  2006-03-15       Impact factor: 9.139
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  13 in total

1.  Obesity in children with poorly controlled asthma: Sex differences.

Authors:  Jason E Lang; Janet T Holbrook; Robert A Wise; Anne E Dixon; W Gerald Teague; Christine Y Wei; Charles G Irvin; David Shade; John J Lima
Journal:  Pediatr Pulmonol       Date:  2012-11-09

Review 2.  Adiponectin in pulmonary disease and critically ill patients.

Authors:  P Garcia; A Sood
Journal:  Curr Med Chem       Date:  2012       Impact factor: 4.530

3.  Leptin treatment reduces body fat but does not affect lean body mass or the myostatin-follistatin-activin axis in lean hypoleptinemic women.

Authors:  Mary Brinkoetter; Faidon Magkos; Maria Vamvini; Christos S Mantzoros
Journal:  Am J Physiol Endocrinol Metab       Date:  2011-04-19       Impact factor: 4.310

4.  Sex differences in the association between neck circumference and asthma.

Authors:  Lisa Maltz; Ethan L Matz; Heather Gordish-Dressman; Dinesh K Pillai; Stephen J Teach; Carlos A Camargo; Monica J Hubal; Simran Behniwal; Guy D Prosper; Nicole Certner; Raman Marwah; Douglas M Mansell; Fisayo Nwachukwu; Risa Lazaroff; Yodit Tsegaye; Robert J Freishtat
Journal:  Pediatr Pulmonol       Date:  2016-01-15

5.  Association of Age at Menarche and Menstrual Characteristics with Adult Onset Asthma among Reproductive Age Women.

Authors:  Neway G Fida; Michelle A Williams; Daniel A Enquobahrie
Journal:  Reprod Syst Sex Disord       Date:  2012-08-31

6.  Adiposity and Asthma in a Nationwide Study of Children and Adults in the United States.

Authors:  Erick Forno; Yueh-Ying Han; Ingrid M Libman; Radhika H Muzumdar; Juan C Celedón
Journal:  Ann Am Thorac Soc       Date:  2018-03

7.  Sex differences in the relationship between asthma and overweight in Dutch children: a survey study.

Authors:  Maartje Willeboordse; Donna L C M van den Bersselaar; Kim D G van de Kant; Jean W M Muris; Onno C P van Schayck; Edward Dompeling
Journal:  PLoS One       Date:  2013-10-17       Impact factor: 3.240

8.  Shared genetic and experimental links between obesity-related traits and asthma subtypes in UK Biobank.

Authors:  Zhaozhong Zhu; Yanjun Guo; Huwenbo Shi; Cong-Lin Liu; Ronald Allan Panganiban; Wonil Chung; Luke J O'Connor; Blanca E Himes; Steven Gazal; Kohei Hasegawa; Carlos A Camargo; Lu Qi; Miriam F Moffatt; Frank B Hu; Quan Lu; William O C Cookson; Liming Liang
Journal:  J Allergy Clin Immunol       Date:  2019-10-24       Impact factor: 10.793

9.  Rapid decline in lung function is temporally associated with greater metabolically active adiposity in a longitudinal study of healthy adults.

Authors:  Maan Moualla; Clifford Qualls; Alexander Arynchyn; Bharat Thyagarajan; Ravi Kalhan; Lewis J Smith; John J Carr; David R Jacobs; Akshay Sood
Journal:  Thorax       Date:  2017-07-20       Impact factor: 9.102

10.  Investigating the association between obesity and asthma in 6- to 8-year-old Saudi children: a matched case-control study.

Authors:  Mahmoud Nahhas; Raj Bhopal; Chantelle Anandan; Rob Elton; Aziz Sheikh
Journal:  NPJ Prim Care Respir Med       Date:  2014-06-05       Impact factor: 2.871
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