Literature DB >> 2108841

Chromosome mapping of the human RAS-related RAP1A, RAP1B, and RAP2 genes to chromosomes 1p12----p13, 12q14, and 13q34, respectively.

M F Rousseau-Merck1, V Pizon, A Tavitian, R Berger.   

Abstract

Three human cDNAs encoding new RAS-related cDNAs, designated RAP1A, RAP1B, and RAP2, have been isolated previously. The encoded proteins are highly related to RAS in the effector region and share an overall identity with RAS of approximately 50%. Using the complete cDNAs or parts thereof as probes, each RAP gene has been localized on human chromosomes by in situ hybridization. The three genes RAP1A, RAP1B, and RAP2 have been assigned to chromosome bands 1p12----p13, 12q14, and 13q34, respectively.

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Year:  1990        PMID： 2108841     DOI： 10.1159/000132883

Source DB:  PubMed          Journal:  Cytogenet Cell Genet        ISSN： 0301-0171


  10 in total

1.  Chromosome assignment of four RAS-related RAB genes.

Authors:  M F Rousseau-Merck; A Zahraoui; N Touchot; A Tavitian; R Berger
Journal:  Hum Genet       Date:  1991-02       Impact factor: 4.132

Review 2.  The role of small GTPases and EPAC-Rap signaling in the regulation of the blood-brain and blood-retinal barriers.

Authors:  Carla J Ramos; David A Antonetti
Journal:  Tissue Barriers       Date:  2017-06-09

Review 3.  Biology of the Rap proteins, members of the ras superfamily of GTP-binding proteins.

Authors:  G M Bokoch
Journal:  Biochem J       Date:  1993-01-01       Impact factor: 3.857

4.  Association between prostate cancer in black Americans and an allele of the PADPRP pseudogene locus on chromosome 13.

Authors:  J A Doll; B K Suarez; H Donis-Keller
Journal:  Am J Hum Genet       Date:  1996-02       Impact factor: 11.025

5.  Rap1 and its regulatory proteins: the tumor suppressor, oncogene, tumor suppressor gene axis in head and neck cancer.

Authors:  Rajat Banerjee; Nickole Russo; Min Liu; Elizabeth Van Tubergen; Nisha J D'Silva
Journal:  Small GTPases       Date:  2012-06-11

6.  ArhGEF12 activates Rap1A and not RhoA in human dermal microvascular endothelial cells to reduce tumor necrosis factor-induced leak.

Authors:  Alamzeb Khan; Weiming Ni; Tania Baltazar; Francesc Lopez-Giraldez; Jordan S Pober; Richard W Pierce
Journal:  FASEB J       Date:  2022-04       Impact factor: 5.834

7.  Rap1b facilitates NK cell functions via IQGAP1-mediated signalosomes.

Authors:  Aradhana Awasthi; Asanga Samarakoon; Haiyan Chu; Rajasekaran Kamalakannan; Lawrence A Quilliam; Magdalena Chrzanowska-Wodnicka; Gilbert C White; Subramaniam Malarkannan
Journal:  J Exp Med       Date:  2010-08-23       Impact factor: 14.307

8.  The EPAC-Rap1 pathway prevents and reverses cytokine-induced retinal vascular permeability.

Authors:  Carla J Ramos; Chengmao Lin; Xuwen Liu; David A Antonetti
Journal:  J Biol Chem       Date:  2017-11-20       Impact factor: 5.157

9.  Rap1b regulates B cell development, homing, and T cell-dependent humoral immunity.

Authors:  Haiyan Chu; Aradhana Awasthi; Gilbert C White; Magdalena Chrzanowska-Wodnicka; Subramaniam Malarkannan
Journal:  J Immunol       Date:  2008-09-01       Impact factor: 5.422

10.  Normal human chromosome 1 carries suppressor activity for various phenotypes of a Kirsten murine sarcoma virus-transformed NIH/3T3 cell line.

Authors:  H Yamada; I Horikawa; H Hashiba; M Oshimura
Journal:  Jpn J Cancer Res       Date:  1990-11
  10 in total

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