Literature DB >> 21088359

Mefloquine treatment in a patient suffering from progressive multifocal leukoencephalopathy after umbilical cord blood transplant.

Shuji Kishida1, Kozue Tanaka.   

Abstract

We report herein the case of a 37-year-old man who developed probable progressive multifocal leukoencephalopathy (PML) following an umbilical cord blood transplant. The patient showed favorable clinical, neuroradiological and virological responses after treatment with mefloquine, an anti-malarial drug. Mefloquine may offer some benefits as a treatment for PML in patients with or without human immunodeficiency virus type-1 infection. This report highlights the need to gather sufficient data to confirm the efficacy of mefloquine against this devastating viral disease of the central nervous system.

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Year:  2010        PMID： 21088359     DOI： 10.2169/internalmedicine.49.3227

Source DB:  PubMed          Journal:  Intern Med        ISSN： 0918-2918            Impact factor:   1.271


  11 in total

Review 1.  Progressive multifocal leukoencephalopathy: clinical and molecular aspects.

Authors:  Eleonora Tavazzi; Martyn K White; Kamel Khalili
Journal:  Rev Med Virol       Date:  2011-09-21       Impact factor: 6.989

2.  Late relapse of progressive multifocal leucoencephalopathy postallogenic transplant in a young patient with CLL.

Authors:  Ana Sanchez-Quintana; Joaquín Breña-Atienza; Carmen Marrero-Santos; Luis Alvarez-Acosta
Journal:  BMJ Case Rep       Date:  2013-08-05

Review 3.  Molecular biology, epidemiology, and pathogenesis of progressive multifocal leukoencephalopathy, the JC virus-induced demyelinating disease of the human brain.

Authors:  Michael W Ferenczy; Leslie J Marshall; Christian D S Nelson; Walter J Atwood; Avindra Nath; Kamel Khalili; Eugene O Major
Journal:  Clin Microbiol Rev       Date:  2012-07       Impact factor: 26.132

4.  Significant improvement following combination treatment with mefloquine and mirtazapine in a patient with progressive multifocal leukoencephalopathy after allogeneic peripheral blood stem cell transplantation.

Authors:  Hitoshi Yoshida; Kenji Ohshima; Jun Toda; Shinsuke Kusakabe; Hiroaki Masaie; Toshinari Yagi; Jun Ishikawa
Journal:  Int J Hematol       Date:  2013-11-22       Impact factor: 2.490

5.  Usefulness of 11C-methionine-positron emission tomography for the diagnosis of progressive multifocal leukoencephalopathy.

Authors:  Shinichi Shirai; Ichiro Yabe; Takahiro Kano; Yuka Shimizu; Toru Sasamori; Kazunori Sato; Makoto Hirotani; Takayuki Nonaka; Ikuko Takahashi; Masaaki Matsushima; Naoya Minami; Kazuo Nakamichi; Masayuki Saijo; Kanako C Hatanaka; Tohru Shiga; Shinya Tanaka; Hidenao Sasaki
Journal:  J Neurol       Date:  2014-09-16       Impact factor: 4.849

Review 6.  Successful treatment of non-HIV progressive multifocal leukoencephalopathy: case report and literature review.

Authors:  Mai Hamaguchi; Keisuke Suzuki; Hiroaki Fujita; Takeo Uzuka; Hadzki Matsuda; Yukiko Shishido-Hara; Satoko Arai; Toshiki Nakamura; Shigeru Kikuchi; Kazuo Nakamichi; Masayuki Saijo; Koichi Hirata
Journal:  J Neurol       Date:  2019-11-14       Impact factor: 6.682

7.  Brain Biopsy Is More Reliable than the DNA test for JC Virus in Cerebrospinal Fluid for the Diagnosis of Progressive Multifocal Leukoencephalopathy.

Authors:  Junji Ikeda; Akira Matsushima; Wataru Ishii; Tetuya Goto; Kenta Takahashi; Kazuo Nakamichi; Masayuki Saijo; Yoshiki Sekijima; Shu-Ichi Ikeda
Journal:  Intern Med       Date:  2017-05-15       Impact factor: 1.271

8.  A loop-mediated isothermal amplification assay for the detection and quantification of JC polyomavirus in cerebrospinal fluid: a diagnostic and clinical management tool and technique for progressive multifocal leukoencephalopathy.

Authors:  Hitomi Kinoshita; Kazuo Nakamichi; Chang-Kweng Lim; Mutsuyo Takayama-Ito; Lixin Wang; Itoe Iizuka; Ichiro Kurane; Masayuki Saijo
Journal:  Virol J       Date:  2018-08-31       Impact factor: 4.099

Review 9.  Human polyomavirus reactivation: disease pathogenesis and treatment approaches.

Authors:  Cillian F De Gascun; Michael J Carr
Journal:  Clin Dev Immunol       Date:  2013-05-02

10.  Simultaneous Development of Progressive Multifocal Leukoencephalopathy and Cryptococcal Meningitis during Methotrexate and Infliximab Treatment.

Authors:  Yasunobu Nosaki; Ken Ohyama; Maki Watanabe; Takamasa Yokoi; Kazuo Nakamichi; Masayuki Saijo; Yoshiharu Miura; Katsushige Iwai
Journal:  Intern Med       Date:  2019-09-15       Impact factor: 1.271
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