BACKGROUND: This study aimed to examine combined and independent effects of cardiorespiratory fitness and fatness on cardiovascular risk factors among U.S. adolescents. METHODS: Data from adolescents age 12 to 19 years participating in the NHANES 1999 to 2002 were used. Fitness level was determined by submaximal treadmill test and was dichotomized as 'not fit' or 'fit' according to the FITNESSGRAM. Fatness level was categorized as 'not fat' or 'fat' based on the CDC BMI growth charts. Gender-specific multivariable linear regression analyses were conducted to compare age-, race/ethnicity-, fatness-, and waist circumference-adjusted means of blood pressure, lipids, lipoproteins, C-peptide, insulin, and C-reactive protein (CRP) levels. RESULTS: A total of 3202 adolescents (1629 boys) were included for data analysis. Among boys, total cholesterol, triglycerides, insulin, and CRP mean levels were significantly higher (P < .05) in the 'not fit' group than in the 'fit' group, after adjustment for fatness level and waist circumference. Among girls, the fatness level- and waist circumference-adjusted means of total cholesterol (P < .01) and LDL-C (P < .09) were higher in the 'not fit' than 'fit' groups. CONCLUSION: Cardiorespiratory fitness, independent of fatness, may have beneficial effects on lipid profiles among girls, and on lipid profiles, insulin metabolism, and inflammation levels among boys.
BACKGROUND: This study aimed to examine combined and independent effects of cardiorespiratory fitness and fatness on cardiovascular risk factors among U.S. adolescents. METHODS: Data from adolescents age 12 to 19 years participating in the NHANES 1999 to 2002 were used. Fitness level was determined by submaximal treadmill test and was dichotomized as 'not fit' or 'fit' according to the FITNESSGRAM. Fatness level was categorized as 'not fat' or 'fat' based on the CDC BMI growth charts. Gender-specific multivariable linear regression analyses were conducted to compare age-, race/ethnicity-, fatness-, and waist circumference-adjusted means of blood pressure, lipids, lipoproteins, C-peptide, insulin, and C-reactive protein (CRP) levels. RESULTS: A total of 3202 adolescents (1629 boys) were included for data analysis. Among boys, total cholesterol, triglycerides, insulin, and CRP mean levels were significantly higher (P < .05) in the 'not fit' group than in the 'fit' group, after adjustment for fatness level and waist circumference. Among girls, the fatness level- and waist circumference-adjusted means of total cholesterol (P < .01) and LDL-C (P < .09) were higher in the 'not fit' than 'fit' groups. CONCLUSION:Cardiorespiratory fitness, independent of fatness, may have beneficial effects on lipid profiles among girls, and on lipid profiles, insulin metabolism, and inflammation levels among boys.
Authors: Yide Yang; Patrick Wc Lau; Jingjing Wang; Bin Dong; Lijing Wu; Binh Quach; Del P Wong; Lianguo Fu; Jun Ma; Haijun Wang Journal: Hypertens Res Date: 2016-06-23 Impact factor: 3.872
Authors: Esther M González-Gil; Alba M Santaliestra-Pasías; Christoph Buck; Luis Gracia-Marco; Fabio Lauria; Valeria Pala; Denes Molnar; Toomas Veidebaum; Licia Iacoviello; Michael Tornaritis; Gabriele Eiben; Lauren Lissner; Heike Schwarz; Wolfgang Ahrens; Stefaan De Henauw; Arno Fraterman; Luis A Moreno Journal: Pediatr Res Date: 2021-04-09 Impact factor: 3.756
Authors: Danladi I Musa; Abel L Toriola; Daniel T Goon; Sunday U Jonathan Journal: Int J Environ Res Public Health Date: 2020-08-13 Impact factor: 3.390