Literature DB >> 2108785

Excitatory effects of thyrotropin-releasing hormone (TRH) in hypoglossal motoneurons.

J C Rekling1.   

Abstract

The effect of thyrotropin-releasing hormone (TRH) was studied in 30 hypoglossal motoneurons from brainstem slices of guinea pigs. Bath application of TRH resulted in an increase of the spontaneous excitatory synaptic activity, depolarization of the neurons, increase of the input resistance and change of the duration of the falling phase of excitatory postsynaptic potentials. The depolarizing response and membrane conductance change was the result of a direct postsynaptic action of TRH, possibly mediated by a reduction of a potassium conductance.

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Year:  1990        PMID： 2108785     DOI： 10.1016/0006-8993(90)90749-2

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  5 in total

Review 1.  Synaptic control of motoneuronal excitability.

Authors:  J C Rekling; G D Funk; D A Bayliss; X W Dong; J L Feldman
Journal:  Physiol Rev       Date:  2000-04       Impact factor: 37.312

Review 2.  Neural Control of the Upper Airway: Respiratory and State-Dependent Mechanisms.

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Journal:  Compr Physiol       Date:  2016-09-15       Impact factor: 9.090

3.  Lung respiratory rhythm and pattern generation in the bullfrog: role of neurokinin-1 and mu-opioid receptors.

Authors:  B L Davies; C M Brundage; M B Harris; B E Taylor
Journal:  J Comp Physiol B       Date:  2009-01-30       Impact factor: 2.200

4.  Differential activating effects of thyrotropin-releasing hormone and its analog taltirelin on motor output to the tongue musculature in vivo.

Authors:  Wen-Ying Liu; Hattie Liu; Jasmin Aggarwal; Zhi-Li Huang; Richard L Horner
Journal:  Sleep       Date:  2020-09-14       Impact factor: 5.849

5.  Modulation of TASK-1/3 channels at the hypoglossal motoneuron pool and effects on tongue motor output and responses to excitatory inputs in vivo: implications for strategies for obstructive sleep apnea pharmacotherapy.

Authors:  Patrick Gurges; Hattie Liu; Richard L Horner
Journal:  Sleep       Date:  2021-01-21       Impact factor: 5.849
  5 in total

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