Literature DB >> 21087512

Small cell carcinoma in ulcerative colitis--new treatment option: a case report.

Christoforos Kosmidis1, Christoforos Efthimiadis, Georgios Anthimidis, Kalliopi Vasiliadou, Ioanna Tzeveleki, Panagiotis Fotiadis, Georgios Basdanis.   

Abstract

BACKGROUND: The most common type of carcinoma associated with ulcerative colitis (UC) is adenocarcinoma. We present a case of primary rectal small cell carcinoma in a patient with a history of UC.
METHODS: A 34-year-old male diagnosed with UC for 10 years was not consistent with the usual annual follow-up and presented with mucoid-bloody diarrhea. Colonoscopy revealed a rectal mass 2 cm distant from the anal verge. The patient underwent a total proctocolectomy with preservation of the anal sphincters, construction of an ileal reservoir, anastomosis of the reservoir to the anus (J configuration) and protective loop ileostomy.
RESULTS: Histological examination showed undifferentiated small cell carcinoma.
CONCLUSIONS: This is the first case of small cell carcinoma in a background of UC reported to be treated surgically and the patient and has no recurrence 18 months postoperatively.

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Year:  2010        PMID: 21087512      PMCID: PMC2999595          DOI: 10.1186/1477-7819-8-100

Source DB:  PubMed          Journal:  World J Surg Oncol        ISSN: 1477-7819            Impact factor:   2.754


  12 in total

1.  The effectiveness of chemotherapy with cisplatin and 5-fluorouracil for recurrent small cell neuroendocrine carcinoma of the rectum: report of a case.

Authors:  T Okuyama; D Korenaga; S Tamura; T Yao; S Maekawa; A Watanabe; T Ikeda; K Sugimachi
Journal:  Surg Today       Date:  1999       Impact factor: 2.549

Review 2.  Risk for colorectal cancer in ulcerative colitis: changes, causes and management strategies.

Authors:  Peter-Laszlo Lakatos; Laszlo Lakatos
Journal:  World J Gastroenterol       Date:  2008-07-07       Impact factor: 5.742

3.  Small cell neuroendocrine carcinoma of the rectum associated with chronic ulcerative colitis.

Authors:  A Rubin; P P Pandya
Journal:  Histopathology       Date:  1990-01       Impact factor: 5.087

4.  Stem cell carcinoma of the colon and rectum. Report of two cases and review of the literature.

Authors:  D H Palvio; F B Sørensen; M Kløve-Mogensen
Journal:  Dis Colon Rectum       Date:  1985-06       Impact factor: 4.585

5.  Cancer surveillance in ulcerative colitis.

Authors:  F W Nugent; R C Haggitt; P A Gilpin
Journal:  Gastroenterology       Date:  1991-05       Impact factor: 22.682

6.  Neuroendocrine carcinoma of the colon and rectum. A clinicopathologic, ultrastructural, and immunohistochemical study of 24 cases.

Authors:  M J Gaffey; S E Mills; E E Lack
Journal:  Am J Surg Pathol       Date:  1990-11       Impact factor: 6.394

7.  Dysplasia in inflammatory bowel disease: standardized classification with provisional clinical applications.

Authors:  R H Riddell; H Goldman; D F Ransohoff; H D Appelman; C M Fenoglio; R C Haggitt; C Ahren; P Correa; S R Hamilton; B C Morson
Journal:  Hum Pathol       Date:  1983-11       Impact factor: 3.466

8.  Small-cell undifferentiated carcinoma of the colon. A clinicopathological study of five cases and their association with colonic adenomas.

Authors:  S E Mills; M S Allen; A R Cohen
Journal:  Am J Surg Pathol       Date:  1983-10       Impact factor: 6.394

9.  Primary small cell undifferentiated carcinoma of the rectum associated with ulcerative colitis.

Authors:  H Yaziji; W L Broghamer
Journal:  South Med J       Date:  1996-09       Impact factor: 0.954

10.  Small cell neuroendocrine carcinoma of the colon and rectum: clinical, histologic, and ultrastructural study and immunohistochemical comparison with cloacogenic carcinoma.

Authors:  M R Wick; R P Weatherby; L H Weiland
Journal:  Hum Pathol       Date:  1987-01       Impact factor: 3.466

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  4 in total

1.  A case of primary colonic small-cell carcinoma arising in a patient with long-standing ulcerative colitis.

Authors:  Renée M Marchioni Beery; Thomas J Devers; Jessica M Clement
Journal:  Gastrointest Cancer Res       Date:  2014-05

2.  Radiation therapy improves survival in rectal small cell cancer - Analysis of Surveillance Epidemiology and End Results (SEER) data.

Authors:  Aram S Modrek; Howard C Hsu; Cynthia G Leichman; Kevin L Du
Journal:  Radiat Oncol       Date:  2015-04-24       Impact factor: 3.481

3.  Metachronous metastatic colonic small cell carcinoma and recurrent adenocarcinoma in a patient with ulcerative colitis.

Authors:  Alexandra W Elias; Dorin T Colibaseanu; Kristopher P Croome
Journal:  J Surg Case Rep       Date:  2017-10-20

Review 4.  A Mixed Neuroendocrine/Non-Neuroendocrine Neoplasm Arising in the Background of Ulcerative Colitis: A Case Report and Review of the Literature.

Authors:  Saud A Al Buthi; Sultanah F Bin Gheshayan; Ibrahim Al Samaani; Bushra Al Ahmadi; Nahar A Al Selaim
Journal:  Am J Case Rep       Date:  2022-03-03
  4 in total

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