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Literature DB >> 21084639

Are oncogenes sufficient to cause human cancer?

Scott E Woodman¹, Gordon B Mills.

Abstract

Entities: Disease Species

Mesh：

Year: 2010 PMID： 21084639 PMCID： PMC2996413 DOI： 10.1073/pnas.1015563107

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

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17 in total

Review 1. FGFR3 mutations and the skin: report of a patient with a FGFR3 gene mutation, acanthosis nigricans, hypochondroplasia and hyperinsulinemia and review of the literature.

Authors: M Blomberg; E M Jeppesen; F Skovby; E Benfeldt
Journal: Dermatology Date: 2010-05-04 Impact factor: 5.366

2. Multiple oncogenic mutations and clonal relationship in spatially distinct benign human epidermal tumors.

Authors: Christian Hafner; Agustí Toll; Alejandro Fernández-Casado; Julie Earl; Miriam Marqués; Francesco Acquadro; Marinela Méndez-Pertuz; Miguel Urioste; Núria Malats; Julie E Burns; Margaret A Knowles; Juan C Cigudosa; Arndt Hartmann; Thomas Vogt; Michael Landthaler; Ramón M Pujol; Francisco X Real
Journal: Proc Natl Acad Sci U S A Date: 2010-11-15 Impact factor: 11.205

Review 3. Senescence in tumours: evidence from mice and humans.

Authors: Manuel Collado; Manuel Serrano
Journal: Nat Rev Cancer Date: 2010-01 Impact factor: 60.716

Review 4. The origins of urothelial carcinoma.

Authors: Liang Cheng; Darrell D Davidson; Gregory T Maclennan; Sean R Williamson; Shaobo Zhang; Michael O Koch; Rodolfo Montironi; Antonio Lopez-Beltran
Journal: Expert Rev Anticancer Ther Date: 2010-06 Impact factor: 4.512

5. Genetics and genomics of melanoma.

Authors: Papia Ghosh; Lynda Chin
Journal: Expert Rev Dermatol Date: 2009-04-01

Review 6. Targeting PI3K signalling in cancer: opportunities, challenges and limitations.

Authors: Jeffrey A Engelman
Journal: Nat Rev Cancer Date: 2009-08 Impact factor: 60.716

7. No mutations of FGFR3 in normal urothelium in the vicinity of urothelial carcinoma of the bladder harbouring activating FGFR3 mutations in patients with bladder cancer.

Authors: Wolfgang Otto; Stefan Denzinger; Simone Bertz; Andreas Gaumann; Peter J Wild; Arndt Hartmann; Robert Stoehr
Journal: Int J Cancer Date: 2009-11-01 Impact factor: 7.396

Review 8. Metastasis of benign tumor cells in tuberous sclerosis complex.

Authors: Elizabeth Petri Henske
Journal: Genes Chromosomes Cancer Date: 2003-12 Impact factor: 5.006

9. Identifying genotype-dependent efficacy of single and combined PI3K- and MAPK-pathway inhibition in cancer.

Authors: Martin L Sos; Stefanie Fischer; Roland Ullrich; Martin Peifer; Johannes M Heuckmann; Mirjam Koker; Stefanie Heynck; Isabel Stückrath; Jonathan Weiss; Florian Fischer; Kathrin Michel; Aviva Goel; Lucia Regales; Katerina A Politi; Samanthi Perera; Matthäus Getlik; Lukas C Heukamp; Sascha Ansén; Thomas Zander; Rameen Beroukhim; Hamid Kashkar; Kevan M Shokat; William R Sellers; Daniel Rauh; Christine Orr; Klaus P Hoeflich; Lori Friedman; Kwok-Kin Wong; William Pao; Roman K Thomas
Journal: Proc Natl Acad Sci U S A Date: 2009-10-05 Impact factor: 11.205

Are oncogenes sufficient to cause human cancer?

Review 1. FGFR3 mutations and the skin: report of a patient with a FGFR3 gene mutation, acanthosis nigricans, hypochondroplasia and hyperinsulinemia and review of the literature.

2. Multiple oncogenic mutations and clonal relationship in spatially distinct benign human epidermal tumors.

Review 3. Senescence in tumours: evidence from mice and humans.

Review 4. The origins of urothelial carcinoma.

5. Genetics and genomics of melanoma.

Review 6. Targeting PI3K signalling in cancer: opportunities, challenges and limitations.

7. No mutations of FGFR3 in normal urothelium in the vicinity of urothelial carcinoma of the bladder harbouring activating FGFR3 mutations in patients with bladder cancer.

Review 8. Metastasis of benign tumor cells in tuberous sclerosis complex.

9. Identifying genotype-dependent efficacy of single and combined PI3K- and MAPK-pathway inhibition in cancer.

10. Braf(V600E) cooperates with Pten loss to induce metastatic melanoma.

Review 1. [Genetic basis of seborrheic keratosis and epidermal nevi].

2. Paradoxical Behavior of Oncogenes Undermines the Somatic Mutation Theory.

Review 3. The promise and perils of causal circuit manipulations.

4. Genetic alterations in seborrheic keratoses.