Literature DB >> 21084474

Viral serine/threonine protein kinases.

Thary Jacob1, Céline Van den Broeke, Herman W Favoreel.   

Abstract

Phosphorylation represents one the most abundant and important posttranslational modifications of proteins, including viral proteins. Virus-encoded serine/threonine protein kinases appear to be a feature that is unique to large DNA viruses. Although the importance of these kinases for virus replication in cell culture is variable, they invariably play important roles in virus virulence. The current review provides an overview of the different viral serine/threonine protein kinases of several large DNA viruses and discusses their function, importance, and potential as antiviral drug targets.

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Year:  2010        PMID： 21084474      PMCID： PMC3020496          DOI： 10.1128/JVI.01369-10

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  237 in total

1.  Temperature-dependent phosphorylation state of the H5R protein synthesised at the early stage of infection in cells infected with vaccinia virus ts mutants of the B1R and F10L protein kinases.

Authors:  G Beaud; R Beaud
Journal:  Intervirology       Date:  2000       Impact factor: 1.763

2.  Isolation, characterization, and physical mapping of temperature-sensitive mutants of vaccinia virus.

Authors:  R C Condit; A Motyczka; G Spizz
Journal:  Virology       Date:  1983-07-30       Impact factor: 3.616

3.  The R1 subunit of herpes simplex virus ribonucleotide reductase is a good substrate for host cell protein kinases but is not itself a protein kinase.

Authors:  Y Langelier; L Champoux; M Hamel; C Guilbault; N Lamarche; P Gaudreau; B Massie
Journal:  J Biol Chem       Date:  1998-01-16       Impact factor: 5.157

4.  Point mutations in BHV-1 Us3 gene abolish its ability to induce cytoskeletal changes in various cell types.

Authors:  Agnieszka Brzozowska; Michał Rychłowski; Andrea D Lipińska; Krystyna Bieńkowska-Szewczyk
Journal:  Vet Microbiol       Date:  2010-02-11       Impact factor: 3.293

5.  Maribavir antagonizes the antiviral action of ganciclovir on human cytomegalovirus.

Authors:  Sunwen Chou; Gail I Marousek
Journal:  Antimicrob Agents Chemother       Date:  2006-10       Impact factor: 5.191

6.  Hyperphosphorylation of histone deacetylase 2 by alphaherpesvirus US3 kinases.

Authors:  Matthew S Walters; Paul R Kinchington; Bruce W Banfield; Saul Silverstein
Journal:  J Virol       Date:  2010-07-21       Impact factor: 5.103

7.  Analysis of filamentous process induction and nuclear localization properties of the HSV-2 serine/threonine kinase Us3.

Authors:  Renée L Finnen; Bibhuti B Roy; Hui Zhang; Bruce W Banfield
Journal:  Virology       Date:  2009-11-28       Impact factor: 3.616

8.  The vaccinia-related kinases phosphorylate the N' terminus of BAF, regulating its interaction with DNA and its retention in the nucleus.

Authors:  R Jeremy Nichols; Matthew S Wiebe; Paula Traktman
Journal:  Mol Biol Cell       Date:  2006-02-22       Impact factor: 4.138

9.  Members of a novel family of mammalian protein kinases complement the DNA-negative phenotype of a vaccinia virus ts mutant defective in the B1 kinase.

Authors:  Kathleen A Boyle; Paula Traktman
Journal:  J Virol       Date:  2004-02       Impact factor: 5.103

10.  Herpes simplex virus type 1 Us3 gene deletion influences toll-like receptor responses in cultured monocytic cells.

Authors:  Piritta Peri; Riikka K Mattila; Helena Kantola; Eeva Broberg; Heidi S Karttunen; Matti Waris; Tytti Vuorinen; Veijo Hukkanen
Journal:  Virol J       Date:  2008-11-21       Impact factor: 4.099
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  45 in total

Review 1.  Trojan horse strategies used by pathogens to influence the small ubiquitin-like modifier (SUMO) system of host eukaryotic cells.

Authors:  Miklós Békés; Marcin Drag
Journal:  J Innate Immun       Date:  2012-01-03       Impact factor: 7.349

2.  Herpes simplex virus 1 protein kinase Us3 phosphorylates viral dUTPase and regulates its catalytic activity in infected cells.

Authors:  Akihisa Kato; Shumpei Tsuda; Zhuoming Liu; Hiroko Kozuka-Hata; Masaaki Oyama; Yasushi Kawaguchi
Journal:  J Virol       Date:  2013-10-30       Impact factor: 5.103

3.  Phosphorylation of a herpes simplex virus 1 dUTPase by a viral protein kinase, Us3, dictates viral pathogenicity in the central nervous system but not at the periphery.

Authors:  Akihisa Kato; Keiko Shindo; Yuhei Maruzuru; Yasushi Kawaguchi
Journal:  J Virol       Date:  2013-12-18       Impact factor: 5.103

4.  Protein kinase inhibitors that inhibit induction of lytic program and replication of Epstein-Barr virus.

Authors:  R Goswami; S Gershburg; A Satorius; E Gershburg
Journal:  Antiviral Res       Date:  2012-10-08       Impact factor: 5.970

5.  Conserved Herpesvirus Kinase ORF36 Activates B2 Retrotransposons during Murine Gammaherpesvirus Infection.

Authors:  Aaron M Schaller; Jessica Tucker; Ian Willis; Britt A Glaunsinger
Journal:  J Virol       Date:  2020-07-01       Impact factor: 5.103

6.  Role of gB and pUS3 in Equine Herpesvirus 1 Transfer between Peripheral Blood Mononuclear Cells and Endothelial Cells: a Dynamic In Vitro Model.

Authors:  Bart Spiesschaert; Björn Goldenbogen; Selina Taferner; Matthias Schade; Medhat Mahmoud; Edda Klipp; Nikolaus Osterrieder; Walid Azab
Journal:  J Virol       Date:  2015-09-16       Impact factor: 5.103

7.  Direct Substrate Identification with an Analog Sensitive (AS) Viral Cyclin-Dependent Kinase (v-Cdk).

Authors:  Angie C Umaña; Satoko Iwahori; Robert F Kalejta
Journal:  ACS Chem Biol       Date:  2017-12-19       Impact factor: 5.100

8.  Deletion of the Vaccinia Virus B1 Kinase Reveals Essential Functions of This Enzyme Complemented Partly by the Homologous Cellular Kinase VRK2.

Authors:  Annabel T Olson; Amber B Rico; Zhigang Wang; Gustavo Delhon; Matthew S Wiebe
Journal:  J Virol       Date:  2017-07-12       Impact factor: 5.103

9.  Human Cytomegalovirus Can Procure Deoxyribonucleotides for Viral DNA Replication in the Absence of Retinoblastoma Protein Phosphorylation.

Authors:  Chad V Kuny; Robert F Kalejta
Journal:  J Virol       Date:  2016-09-12       Impact factor: 5.103

10.  Discovery of a Coregulatory Interaction between Kaposi's Sarcoma-Associated Herpesvirus ORF45 and the Viral Protein Kinase ORF36.

Authors:  Denis Avey; Sarah Tepper; Benjamin Pifer; Amritpal Bahga; Hunter Williams; Joseph Gillen; Wenwei Li; Sarah Ogden; Fanxiu Zhu
Journal:  J Virol       Date:  2016-06-10       Impact factor: 5.103
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