| Literature DB >> 21084385 |
Saira Hameed1, Channa N Jayasena, Waljit S Dhillo.
Abstract
The kisspeptins are a family of peptide hormones, which in recent years have been shown to play a critical role in the regulation of the hypothalamic-pituitary-gonadal axis, thus in turn influencing fertility and reproduction. This review examines the physiological role of kisspeptin and the kisspeptin receptor in the control of gonadotrophin and gonadal steroid hormone secretion and the implications of these findings with respect to fertility. In addition, the potential therapeutic use of kisspeptin in the treatment of reproductive disorders will be examined.Entities:
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Year: 2010 PMID: 21084385 DOI: 10.1677/JOE-10-0265
Source DB: PubMed Journal: J Endocrinol ISSN: 0022-0795 Impact factor: 4.286