Literature DB >> 21084010

Adverse reactions in whole blood donors: an Indian scenario.

Chintamani Pathak1, Meenu Pujani, Sangeeta Pahuja, Manjula Jain.   

Abstract

BACKGROUND: Whole blood donation is generally considered to be a safe procedure, but occasionally adverse reactions of varying severity may occur during or at the end of the collection. The aim of the study was to estimate the frequency and type of adverse events occurring during blood donation and to assess the practices which would help to minimise them.
MATERIALS AND METHODS: This retrospective single-centre study was conducted from June 2007 to November 2009 at a regional blood transfusion centre. All whole blood donations made at the centre were analysed. All adverse events occurring during or at the end of donation were noted using a standardised format.
RESULTS: Overall 113 adverse events were reported in relation to 19,045 donations, resulting in an overall adverse event rate of 0.6%, that is, an incidence of 1 in every 166 donations. Presyncopal symptoms, in other words vasovagal reactions of mild intensity, were the most commonly observed adverse reactions and accounted for approximately 70% of all adverse reactions noted.
CONCLUSIONS: Only 0.6% of blood donations were complicated by adverse events and most of these events were presyncopal symptoms. Our study reinforces the fact that blood donation is a very safe procedure which could be made even more event-free by following certain friendly, reassuring and tactful practices.

Entities:  

Mesh:

Year:  2010        PMID: 21084010      PMCID: PMC3021397          DOI: 10.2450/2010.0002-10

Source DB:  PubMed          Journal:  Blood Transfus        ISSN: 1723-2007            Impact factor:   3.443


  10 in total

Review 1.  Blood donor complications after whole-blood donation.

Authors:  Bruce H Newman
Journal:  Curr Opin Hematol       Date:  2004-09       Impact factor: 3.284

2.  Complications related to blood donation: a population-based study.

Authors:  B S Sorensen; S P Johnsen; J Jorgensen
Journal:  Vox Sang       Date:  2007-11-19       Impact factor: 2.144

3.  The consequences of temporary deferral on future whole blood donation.

Authors:  Brian Custer; Artina Chinn; Nora V Hirschler; Michael P Busch; Edward L Murphy
Journal:  Transfusion       Date:  2007-08       Impact factor: 3.157

4.  Adverse reactions during voluntary donation of blood and/or blood components. A statistical-epidemiological study.

Authors:  Antonio Crocco; Domenico D'Elia
Journal:  Blood Transfus       Date:  2007-07       Impact factor: 3.443

5.  Adverse reactions in blood and apheresis donors: experience from two Italian transfusion centres.

Authors:  Isabella Crocco; Massimo Franchini; Giovanni Garozzo; Anna Rosa Gandini; Giorgio Gandini; Pietro Bonomo; Giuseppe Aprili
Journal:  Blood Transfus       Date:  2009-01       Impact factor: 3.443

6.  Adverse reactions to blood donations: the READ project.

Authors:  Giovanni Garozzo; Isabella Crocco; Barbara Giussani; Annalisa Martinucci; Stefano Monacelli; Vanda Randi
Journal:  Blood Transfus       Date:  2010-01       Impact factor: 3.443

7.  Vasovagal symptoms mediate the relationship between predonation anxiety and subsequent blood donation in female volunteers.

Authors:  Blaine Ditto; Christopher R France
Journal:  Transfusion       Date:  2006-06       Impact factor: 3.157

8.  Blood donation-related neurologic needle injury: evaluation of 2 years' worth of data from a large blood center.

Authors:  B H Newman; D A Waxman
Journal:  Transfusion       Date:  1996-03       Impact factor: 3.157

9.  Adverse reactions to allogeneic whole blood donation by 16- and 17-year-olds.

Authors:  Anne F Eder; Christopher D Hillyer; Beth A Dy; Edward P Notari; Richard J Benjamin
Journal:  JAMA       Date:  2008-05-21       Impact factor: 56.272

10.  Faint and prefaint reactions in whole-blood donors: an analysis of predonation measurements and their predictive value.

Authors:  Thomas B Wiltbank; Gerald F Giordano; Hany Kamel; Peter Tomasulo; Brian Custer
Journal:  Transfusion       Date:  2008-05-14       Impact factor: 3.157

  10 in total
  11 in total

1.  Vasovagal reactions in whole blood donors at three REDS-II blood centers in Brazil.

Authors:  Thelma T Gonçalez; Ester C Sabino; Karen S Schlumpf; David J Wright; Silvana Leao; Divaldo Sampaio; Pedro L Takecian; Anna B Proietti; Anna B Proitetti; Edward Murphy; Michael Busch; Brian Custer
Journal:  Transfusion       Date:  2011-11-11       Impact factor: 3.157

2.  Adverse Reactions in Allogeneic Blood Donors: A Tertiary Care Experience from a Developing Country.

Authors:  Sadia Sultan; Mohammad Amjad Baig; Syed Mohammed Irfan; Syed Ijlal Ahmed; Syeda Faiza Hasan
Journal:  Oman Med J       Date:  2016-03

3.  Study of adverse whole blood donor reactions in normal healthy blood donors: experience of tertiary health care centre in jammu region.

Authors:  Ashu Dogra; Meena Sidhu; Mitu Dogra; Tilak Raj Raina
Journal:  Indian J Hematol Blood Transfus       Date:  2014-05-08       Impact factor: 0.900

4.  Deferrals of volunteer stem cell donors referred for evaluation for matched-unrelated stem cell donation.

Authors:  S Bräuninger; K Thorausch; B Luxembourg; M Schulz; K U Chow; E Seifried; H Bonig
Journal:  Bone Marrow Transplant       Date:  2014-08-04       Impact factor: 5.483

5.  A Study on the Effect of Pre-donation Salt Loading on Vasovagal Reactions in Young College Going Whole Blood Donors.

Authors:  Suchet Sachdev; Lakhvinder Singh; Ratti Ram Sharma; Neelam Marwaha
Journal:  Indian J Hematol Blood Transfus       Date:  2017-02-07       Impact factor: 0.900

6.  A single-centre study of vasovagal reaction in blood donors: Influence of age, sex, donation status, weight, total blood volume and volume of blood collected.

Authors:  Joseph Philip; R S Sarkar; Neelesh Jain
Journal:  Asian J Transfus Sci       Date:  2014-01

7.  Complications related to blood donation: A multicenter study of the prevalence and influencing factors in voluntary blood donation camps in Karnataka, India.

Authors:  Rajat Kumar Agarwal; Sundar Periyavan; Rakesh Dhanya; Lalith G Parmar; Amit Sedai; Kumari Ankita; Arpit Vaish; Ritesh Sharma; Prabha Gowda
Journal:  Asian J Transfus Sci       Date:  2016 Jan-Jun

Review 8.  Biovigilance: A Global Perspective.

Authors:  Sukhjinder Singh; Shammy Chandel; Phulen Sarma; Dibbanti Harikrishna Reddy; Abhishek Mishra; Subodh Kumar; Prasad Thota; Kotni Murali; Ajay Prakash; Bikash Medhi
Journal:  Perspect Clin Res       Date:  2019 Oct-Dec

9.  National blood donor vigilance programme of India: Analysis of donor adverse reactions reported during initial 2 years of implementation (2016 and 2017).

Authors:  Akanksha Bisht; Neelam Marwaha; Satyam Arora; Gopal K Patidar; Reba Chhabra
Journal:  Asian J Transfus Sci       Date:  2021-06-12

10.  Negative peri-donation events among whole blood donors in a blood bank in Ibadan, Nigeria.

Authors:  Foluke A Fasola
Journal:  J Public Health Afr       Date:  2017-12-31
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