| Literature DB >> 21082810 |
Ya-Ling Chiu1, Show-An Chen, Jean-Hong Chen, Ko-Jie Chen, Hsin-Lung Chen, Hsing-Wen Sung.
Abstract
A dual-emission nanoprobe that can sense changes in the environmental pH is designed based on the concept of pH-responsive Förster resonance energy transfer induced by the conformational transition of an associating polyelectrolyte, N-palmitoyl chitosan, bearing a donor (Cy3) or an acceptor (Cy5) moiety. We demonstrate that the developed pH-responsive nanoprobe can be used to ratiometrically image and thus discriminate the pH changes in the biological environment at different length scales.Entities:
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Year: 2010 PMID： 21082810 DOI： 10.1021/nn102644u
Source DB: PubMed Journal: ACS Nano ISSN： 1936-0851 Impact factor: 15.881