PURPOSE: To investigate the relationship between refractive error and ocular biometry in healthy subjects using a new optical low coherence reflectometry device. METHODS: Biometric measurements were obtained with a LenStar LS 900 (Haag Streit, Switzerland) on one eye of 70 phakic subjects (mean ± SD age; 29 ± 9 years). Forty myopes and 30 non-myopes (best sphere range -9.63 D to +0.63 D) were included. Outcome measures were compared for the two groups using one way between groups ANOVA. These included; keratometry, central corneal thickness, iris width, anterior chamber depth, pupil diameter, lens thickness, axial length and retinal thickness. No mydriatic or cycloplegic agents were used. RESULTS: There were significant differences between groups for keratometry readings (p = 0.021 and p = 0.038 for steep and flat k readings respectively), anterior chamber depth (p = 0.001), lens thickness (p = 0.026) and axial length (p<0.001). As expected significant correlations were found between spherical equivalent power and axial length (Pearson product-moment correlation r = -0.75, p<0.001) and between spherical equivalent power and anterior chamber depth (r = -0.29, p = 0.018). Anterior chamber depth and pupil diameter decreased with age (r = -0.429, p<0.001 and r = -0.386, p = 0.001 respectively) whereas lens thickness increased with age (r = 0.618, p < 0.001). CONCLUSIONS: Our data showed significant differences between myopes and non-myopes for the key biometric parameters assessed and provides information about the relationships between these biometric parameters and age. The results, coupled with a unique ability to image and analyse the ocular structures non-invasively make the LenStar a promising new instrument for ocular evaluation in research and clinical practice.
PURPOSE: To investigate the relationship between refractive error and ocular biometry in healthy subjects using a new optical low coherence reflectometry device. METHODS: Biometric measurements were obtained with a LenStar LS 900 (Haag Streit, Switzerland) on one eye of 70 phakic subjects (mean ± SD age; 29 ± 9 years). Forty myopes and 30 non-myopes (best sphere range -9.63 D to +0.63 D) were included. Outcome measures were compared for the two groups using one way between groups ANOVA. These included; keratometry, central corneal thickness, iris width, anterior chamber depth, pupil diameter, lens thickness, axial length and retinal thickness. No mydriatic or cycloplegic agents were used. RESULTS: There were significant differences between groups for keratometry readings (p = 0.021 and p = 0.038 for steep and flat k readings respectively), anterior chamber depth (p = 0.001), lens thickness (p = 0.026) and axial length (p<0.001). As expected significant correlations were found between spherical equivalent power and axial length (Pearson product-moment correlation r = -0.75, p<0.001) and between spherical equivalent power and anterior chamber depth (r = -0.29, p = 0.018). Anterior chamber depth and pupil diameter decreased with age (r = -0.429, p<0.001 and r = -0.386, p = 0.001 respectively) whereas lens thickness increased with age (r = 0.618, p < 0.001). CONCLUSIONS: Our data showed significant differences between myopes and non-myopes for the key biometric parameters assessed and provides information about the relationships between these biometric parameters and age. The results, coupled with a unique ability to image and analyse the ocular structures non-invasively make the LenStar a promising new instrument for ocular evaluation in research and clinical practice.
Authors: Teresa Ferrer-Blasco; Alberto Domínguez-Vicent; José J Esteve-Taboada; Miguel A Aloy; Jose E Adsuara; Robert Montés-Micó Journal: Graefes Arch Clin Exp Ophthalmol Date: 2016-11-30 Impact factor: 3.117
Authors: Hassan Hashemi; Mehdi Khabazkhoob; Mohammad Hassan Emamian; Mohammad Shariati; Mohammad Miraftab; Abbasali Yekta; Hadi Ostadimoghaddam; Akbar Fotouhi Journal: J Ophthalmic Vis Res Date: 2015 Jul-Sep