Literature DB >> 21080125

Interferon-α and zidovudine for relapsed/refractory adult T cell leukemia/lymphoma: case reports of Japanese patients.

Kenji Ishitsuka1, Hiroo Katsuya, Tomona Toyota, Masanao Ishizu, Naoko Kunami, Mana Fujita, Hidenori Sasaki, Yasushi Takamatsu, Masanobu Uchiyama, Haruo Fujikane, Kentaro Ogata, Shuuji Hara, Kazuo Tamura.   

Abstract

Combination therapy with interferon-α and zidovudine (IFN/AZT) has been regarded as standard care for acute and indolent (i.e., chronic and smouldering) ATL based on reports involving a limited number of patients. This treatment approach has not been evaluated in Japan, a major endemic area of this disease in the world. This is the first Japanese report of IFN/AZT for ATL. It is impossible to draw any definitive conclusion from this small study; however, IFN/AZT showed clear anti-ATL effects for refractory/relapsed ATL patients. This report would contribute for developing future ATL treatment in Japan.

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Year:  2010        PMID: 21080125     DOI: 10.1007/s12185-010-0717-3

Source DB:  PubMed          Journal:  Int J Hematol        ISSN: 0925-5710            Impact factor:   2.490


  8 in total

1.  Granulocyte colony-stimulating factor production by adult T-cell leukaemia cells.

Authors:  K Matsushita; N Arima; K Yamaguchi; T Matsumoto; H Ohtsubo; S Hidaka; H Fujiwara; K Arimura; T Kukita; Y Tokito; A Ozaki; C Tei
Journal:  Br J Haematol       Date:  2000-10       Impact factor: 6.998

2.  Brief report: treatment of adult T-cell leukemia-lymphoma with zidovudine and interferon alfa.

Authors:  O Hermine; D Bouscary; A Gessain; P Turlure; V Leblond; N Franck; A Buzyn-Veil; B Rio; E Macintyre; F Dreyfus
Journal:  N Engl J Med       Date:  1995-06-29       Impact factor: 91.245

3.  Meta-analysis on the use of zidovudine and interferon-alfa in adult T-cell leukemia/lymphoma showing improved survival in the leukemic subtypes.

Authors:  Ali Bazarbachi; Yves Plumelle; Juan Carlos Ramos; Patricia Tortevoye; Zaher Otrock; Graham Taylor; Antoine Gessain; William Harrington; Gérard Panelatti; Olivier Hermine
Journal:  J Clin Oncol       Date:  2010-06-28       Impact factor: 44.544

4.  Erratic zidovudine bioavailability in HIV seropositive patients.

Authors:  K A Macnab; M J Gill; L R Sutherland; N De Boer Visser; D Church
Journal:  J Antimicrob Chemother       Date:  1993-03       Impact factor: 5.790

5.  Treatment of adult T-cell leukemia-lymphoma with a combination of interferon alfa and zidovudine.

Authors:  P S Gill; W Harrington; M H Kaplan; R C Ribeiro; J M Bennett; H A Liebman; M Bernstein-Singer; B M Espina; L Cabral; S Allen
Journal:  N Engl J Med       Date:  1995-06-29       Impact factor: 91.245

6.  Definition, prognostic factors, treatment, and response criteria of adult T-cell leukemia-lymphoma: a proposal from an international consensus meeting.

Authors:  Kunihiro Tsukasaki; Olivier Hermine; Ali Bazarbachi; Lee Ratner; Juan Carlos Ramos; William Harrington; Deirdre O'Mahony; John E Janik; Achiléa L Bittencourt; Graham P Taylor; Kazunari Yamaguchi; Atae Utsunomiya; Kensei Tobinai; Toshiki Watanabe
Journal:  J Clin Oncol       Date:  2008-12-08       Impact factor: 44.544

7.  A prospective phase II clinical trial with the use of zidovudine and interferon-alpha in the acute and lymphoma forms of adult T-cell leukemia/lymphoma.

Authors:  Olivier Hermine; Isabelle Allard; Vincent Lévy; Bertrand Arnulf; Antoine Gessain; Ali Bazarbachi
Journal:  Hematol J       Date:  2002

Review 8.  Treatment of adult T-cell leukemia/lymphoma: past, present, and future.

Authors:  Kenji Ishitsuka; Kazuo Tamura
Journal:  Eur J Haematol       Date:  2007-12-10       Impact factor: 2.997

  8 in total
  2 in total

Review 1.  "Antivirals" in the treatment of adult T cell leukaemia- lymphoma (ATLL).

Authors:  Paul A Fields; Graham P Taylor
Journal:  Curr Hematol Malig Rep       Date:  2012-12       Impact factor: 3.952

Review 2.  Controversies in targeted therapy of adult T cell leukemia/lymphoma: ON target or OFF target effects?

Authors:  Rihab Nasr; Hiba El Hajj; Youmna Kfoury; Hugues de Thé; Olivier Hermine; Ali Bazarbachi
Journal:  Viruses       Date:  2011-06-14       Impact factor: 5.048

  2 in total

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