Literature DB >> 21079942

Borderline low conus medullaris on infant lumbar sonography: what is the clinical outcome and the role of neuroimaging follow-up?

Neil H Thakur1, Lisa H Lowe.   

Abstract

BACKGROUND: Isolated borderline low conus medullaris is a frequent finding on screening lumbar sonography of unknown significance that often prompts further imaging and clinical follow-up.
OBJECTIVE: To determine the clinical outcome and utility of follow-up neuroimaging in infants with isolated borderline low conus on lumbar sonography.
MATERIALS AND METHODS: We reviewed 748 consecutive spinal sonograms identifying infants with conus terminating between L2-L3 disc space and mid-L3 level without other findings of tethered cord. We excluded infants with conditions associated with developmental delay and those who passed away, and compared the age of gross motor milestone achievement to normal ranges. Follow-up imaging was reviewed.
RESULTS: Isolated borderline low conus was found in 90 of 748 infants (12%) on sonography. Seventy of those infants met inclusion criteria. Follow-up imaging in 11 children (10 MRI, 1 sonogram), showed change in conus position to "normal" level in 10, no change in 1, and no new findings within lumbar spine. Clinical follow-up was available in 50 of 70 (71%) children meeting inclusion criteria, with normal motor milestones met in all 50 children.
CONCLUSION: Isolated borderline low conus is a common finding in infants who meet normal developmental milestones suggesting that follow-up evaluation has little utility and is likely unwarranted.

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Year:  2010        PMID: 21079942     DOI: 10.1007/s00247-010-1889-y

Source DB:  PubMed          Journal:  Pediatr Radiol        ISSN: 0301-0449


  12 in total

Review 1.  Spinal ultrasound in infants.

Authors:  E A Dick; K Patel; C M Owens; R De Bruyn
Journal:  Br J Radiol       Date:  2002-04       Impact factor: 3.039

2.  Level of conus medullaris in term and preterm neonates.

Authors:  F Sahin; M Selçuki; N Ecin; A Zenciroğlu; A Unlü; F Yilmaz; N Maviş; S Saribaş
Journal:  Arch Dis Child Fetal Neonatal Ed       Date:  1997-07       Impact factor: 5.747

3.  John Caffey award. MR imaging determination of the location of the normal conus medullaris throughout childhood.

Authors:  D A Wilson; J R Prince
Journal:  AJR Am J Roentgenol       Date:  1989-05       Impact factor: 3.959

Review 4.  Sonography of the neonatal spine: part 2, Spinal disorders.

Authors:  Lisa H Lowe; Andrew J Johanek; Charlotte W Moore
Journal:  AJR Am J Roentgenol       Date:  2007-03       Impact factor: 3.959

Review 5.  Sonography of the neonatal spine: part 1, Normal anatomy, imaging pitfalls, and variations that may simulate disorders.

Authors:  Lisa H Lowe; Andrew J Johanek; Charlotte W Moore
Journal:  AJR Am J Roentgenol       Date:  2007-03       Impact factor: 3.959

6.  Occult spinal dysraphism in neonates: assessment of high-risk cutaneous stigmata on sonography.

Authors:  V M Kriss; N S Desai
Journal:  AJR Am J Roentgenol       Date:  1998-12       Impact factor: 3.959

7.  The vertebral level of termination of the spinal cord during normal and abnormal development.

Authors:  A J Barson
Journal:  J Anat       Date:  1970-05       Impact factor: 2.610

Review 8.  US of the spinal cord in newborns: spectrum of normal findings, variants, congenital anomalies, and acquired diseases.

Authors:  K M Unsinn; T Geley; M C Freund; I Gassner
Journal:  Radiographics       Date:  2000 Jul-Aug       Impact factor: 5.333

9.  Isolated filar cyst on lumbar spine sonography in infants: a case-control study.

Authors:  Neville Irani; Asha R Goud; Lisa H Lowe
Journal:  Pediatr Radiol       Date:  2006-10-06

10.  The conus medullaris: normal US findings throughout childhood.

Authors:  M A DiPietro
Journal:  Radiology       Date:  1993-07       Impact factor: 11.105

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  6 in total

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5.  Ascent of the conus medullaris in human foetuses: a systematic review and meta-analysis.

Authors:  Lucas Costa Almeida; Yasmin Juliany de Souza Figueiredo; André Pinheiro Zylberman; Diogo Costa Garção
Journal:  Sci Rep       Date:  2022-07-25       Impact factor: 4.996

6.  Outcome of ultrasonographic imaging in infants with sacral dimple.

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