Literature DB >> 21079695

Using femtosecond laser to fabricate highly precise interior three-dimensional microstructures in polymeric flow chip.

Chia-Yu Lee, Ting-Chou Chang, Shau-Chun Wang, Chih-Wei Chien, Chung-Wei Cheng.   

Abstract

This paper reports using femtosecond laser marker to fabricate the three-dimensional interior microstructures in one closed flow channel of plastic substrate. Strip-like slots in the dimensions of 800 μm×400 μm×65 μm were ablated with pulse Ti:sapphire laser at 800 nm (pulse duration of ∼120 fs with 1 kHz repetition rate) on acrylic slide. After ablation, defocused beams were used to finish the surface of microstructures. Having finally polished with sonication, the laser fabricated structures are highly precise with the arithmetic roughness of 1.5 and 4.5 nm. Fabricating such highly precise microstructures cannot be accomplished with nanosecond laser marking or other mechanical drilling methods. In addition, since laser ablation can directly engrave interior microstructures in one closed chip, glue smearing problems to damage molded microstructures possibly to occur during the chip sealing procedures can be avoided too.

Year:  2010        PMID: 21079695      PMCID: PMC2980539          DOI: 10.1063/1.3504970

Source DB:  PubMed          Journal:  Biomicrofluidics        ISSN: 1932-1058            Impact factor:   2.800


  4 in total

1.  Femtosecond laser fabrication of tubular waveguides in poly(methyl methacrylate).

Authors:  Arnaud Zoubir; Cedric Lopez; Martin Richardson; Kathleen Richardson
Journal:  Opt Lett       Date:  2004-08-15       Impact factor: 3.776

2.  Photochemistry of refractive index structures in poly(methyl methacrylate) by femtosecond laser irradiation.

Authors:  Alexandra Baum; Patricia J Scully; Maria Basanta; C L Paul Thomas; Peter R Fielden; Nicholas J Goddard; Walter Perrie; Paul R Chalker
Journal:  Opt Lett       Date:  2007-01-15       Impact factor: 3.776

3.  Using ac-field-induced electro-osmosis to accelerate biomolecular binding in fiber-optic sensing chips with microstructures.

Authors:  Yen Chuang; Chia-Yu Lee; Sin-Hong Lu; Shau-Chun Wang; Lai-Kwan Chau; Wen-Hsin Hsieh
Journal:  Anal Chem       Date:  2010-02-01       Impact factor: 6.986

4.  Single femtosecond pulse holography using polymethyl methacrylate.

Authors:  Yan Li; Kazuhiro Yamada; Tomohiko Ishizuka; Wataru Watanabe; Kazuyoshi Itoh; Zhongxiang Zhou
Journal:  Opt Express       Date:  2002-10-21       Impact factor: 3.894

  4 in total
  2 in total

1.  A parallel microfluidic channel fixture fabricated using laser ablated plastic laminates for electrochemical and chemiluminescent biodetection of DNA.

Authors:  Thayne L Edwards; Jason C Harper; Ronen Polsky; Deanna M Lopez; David R Wheeler; Amy C Allen; Susan M Brozik
Journal:  Biomicrofluidics       Date:  2011-12-15       Impact factor: 2.800

2.  Fabrication of pillared PLGA microvessel scaffold using femtosecond laser ablation.

Authors:  Hsiao-Wei Wang; Chung-Wei Cheng; Ching-Wen Li; Han-Wei Chang; Ping-Han Wu; Gou-Jen Wang
Journal:  Int J Nanomedicine       Date:  2012-04-10
  2 in total

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