Literature DB >> 21079426

'Team up against TB': promoting involvement in Thibela TB, a trial of community-wide tuberculosis preventive therapy.

Alison D Grant1, Leonie Coetzee, Katherine L Fielding, James J Lewis, Smanga Ntshele, Mariëtha M Luttig, Kathryn T Mngadi, Dorothy Muller, Flora Popane, John Mdluli, Nkosinathi Mngadi, Clement Sefuthi, David A Clark, Gavin Churchyard.   

Abstract

OBJECTIVE: To describe a programme of community education and mobilization to promote uptake in a cluster-randomized trial of tuberculosis preventive therapy offered to all members of intervention clusters. SETTING AND PARTICIPANTS: Gold mines in South Africa, where tuberculosis incidence is extremely high, despite conventional control measures. All employees in intervention clusters (mine shaft and associated hostel) were invited to enrol. MAIN OUTCOME MEASURE: Cumulative enrolment in the study in intervention clusters.
RESULTS: Key steps in communicating information relevant to the study included extensive consultation with key stakeholders; working with a communication company to develop a project 'brand'; developing a communication strategy tailored to each intervention site; and involving actors from a popular television comedy series to help inform communities about the study. One-to-one communications used peer educators along with study staff, and participant advisory groups facilitated two-way communication between study staff and participants. By contrast, treatment 'buddies' and text messaging to promote adherence proved less successful. Mean cumulative enrolment in the first four intervention clusters was 61.9%, increasing to 83.0% in the final four clusters.
CONCLUSION: A tailored communication strategy can facilitate a high level of enrolment in a community health intervention.

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Year:  2010        PMID: 21079426     DOI: 10.1097/01.aids.0000391020.10661.eb

Source DB:  PubMed          Journal:  AIDS        ISSN: 0269-9370            Impact factor:   4.177


  4 in total

Review 1.  Research on implementation of interventions in tuberculosis control in low- and middle-income countries: a systematic review.

Authors:  Frank Cobelens; Sanne van Kampen; Eleanor Ochodo; Rifat Atun; Christian Lienhardt
Journal:  PLoS Med       Date:  2012-12-18       Impact factor: 11.069

Review 2.  Reminder systems to improve patient adherence to tuberculosis clinic appointments for diagnosis and treatment.

Authors:  Qin Liu; Katharine Abba; Marissa M Alejandria; David Sinclair; Vincent M Balanag; Mary Ann D Lansang
Journal:  Cochrane Database Syst Rev       Date:  2014-11-18

3.  Informed consent and community engagement in open field research: lessons for gene drive science.

Authors:  Jerome Amir Singh
Journal:  BMC Med Ethics       Date:  2019-07-27       Impact factor: 2.652

4.  The timing of tuberculosis after isoniazid preventive therapy among gold miners in South Africa: a prospective cohort study.

Authors:  Sabine M Hermans; Alison D Grant; Violet Chihota; James J Lewis; Emilia Vynnycky; Gavin J Churchyard; Katherine L Fielding
Journal:  BMC Med       Date:  2016-03-23       Impact factor: 8.775

  4 in total

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