Literature DB >> 21079054

Is ticagrelor the antiplatelet therapy panacea?

Amber L Beitelshees.   

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Year:  2010        PMID： 21079054      PMCID： PMC3052795          DOI： 10.1161/CIRCGENETICS.110.958611

Source DB:  PubMed          Journal:  Circ Cardiovasc Genet        ISSN： 1942-3268


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  13 in total

1.  First analysis of the relation between CYP2C19 genotype and pharmacodynamics in patients treated with ticagrelor versus clopidogrel: the ONSET/OFFSET and RESPOND genotype studies.

Authors:  Udaya S Tantry; Kevin P Bliden; Cheryl Wei; Robert F Storey; Martin Armstrong; Kathleen Butler; Paul A Gurbel
Journal:  Circ Cardiovasc Genet       Date:  2010-11-15

2.  Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation.

Authors:  S Yusuf; F Zhao; S R Mehta; S Chrolavicius; G Tognoni; K K Fox
Journal:  N Engl J Med       Date:  2001-08-16       Impact factor: 91.245

3.  Response to ticagrelor in clopidogrel nonresponders and responders and effect of switching therapies: the RESPOND study.

Authors:  Paul A Gurbel; Kevin P Bliden; Kathleen Butler; Mark J Antonino; Cheryl Wei; Renli Teng; Lars Rasmussen; Robert F Storey; Tonny Nielsen; John W Eikelboom; Georges Sabe-Affaki; Steen Husted; Dean J Kereiakes; David Henderson; Dharmendra V Patel; Udaya S Tantry
Journal:  Circulation       Date:  2010-03-01       Impact factor: 29.690

4.  Absorption, distribution, metabolism, and excretion of ticagrelor in healthy subjects.

Authors:  Renli Teng; Stuart Oliver; Martin A Hayes; Kathleen Butler
Journal:  Drug Metab Dispos       Date:  2010-06-15       Impact factor: 3.922

5.  Genetic variants in ABCB1 and CYP2C19 and cardiovascular outcomes after treatment with clopidogrel and prasugrel in the TRITON-TIMI 38 trial: a pharmacogenetic analysis.

Authors:  Jessica L Mega; Sandra L Close; Stephen D Wiviott; Lei Shen; Joseph R Walker; Tabassome Simon; Elliott M Antman; Eugene Braunwald; Marc S Sabatine
Journal:  Lancet       Date:  2010-10-16       Impact factor: 79.321

6.  Effect of CYP2C19 and ABCB1 single nucleotide polymorphisms on outcomes of treatment with ticagrelor versus clopidogrel for acute coronary syndromes: a genetic substudy of the PLATO trial.

Authors:  Lars Wallentin; Stefan James; Robert F Storey; Martin Armstrong; Bryan J Barratt; Jay Horrow; Steen Husted; Hugo Katus; P Gabriel Steg; Svati H Shah; Richard C Becker
Journal:  Lancet       Date:  2010-10-16       Impact factor: 79.321

7.  Ticagrelor versus clopidogrel in patients with acute coronary syndromes.

Authors:  Lars Wallentin; Richard C Becker; Andrzej Budaj; Christopher P Cannon; Håkan Emanuelsson; Claes Held; Jay Horrow; Steen Husted; Stefan James; Hugo Katus; Kenneth W Mahaffey; Benjamin M Scirica; Allan Skene; Philippe Gabriel Steg; Robert F Storey; Robert A Harrington; Anneli Freij; Mona Thorsén
Journal:  N Engl J Med       Date:  2009-08-30       Impact factor: 91.245

8.  Randomized double-blind assessment of the ONSET and OFFSET of the antiplatelet effects of ticagrelor versus clopidogrel in patients with stable coronary artery disease: the ONSET/OFFSET study.

Authors:  Paul A Gurbel; Kevin P Bliden; Kathleen Butler; Udaya S Tantry; Tania Gesheff; Cheryl Wei; Renli Teng; Mark J Antonino; Shankar B Patil; Arun Karunakaran; Dean J Kereiakes; Cordel Parris; Drew Purdy; Vance Wilson; Gary S Ledley; Robert F Storey
Journal:  Circulation       Date:  2009-11-18       Impact factor: 29.690

9.  Which platelet function test is suitable to monitor clopidogrel responsiveness? A pharmacokinetic analysis on the active metabolite of clopidogrel.

Authors:  H J Bouman; E Parlak; J W van Werkum; N J Breet; H ten Cate; C M Hackeng; J M ten Berg; D Taubert
Journal:  J Thromb Haemost       Date:  2009-12-21       Impact factor: 5.824

10.  Functional polymorphisms of the human multidrug-resistance gene: multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo.

Authors:  S Hoffmeyer; O Burk; O von Richter; H P Arnold; J Brockmöller; A Johne; I Cascorbi; T Gerloff; I Roots; M Eichelbaum; U Brinkmann
Journal:  Proc Natl Acad Sci U S A       Date:  2000-03-28       Impact factor: 11.205
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