Literature DB >> 21078738

Iatrogenic events in neonates: beneficial effects of prevention strategies and continuous monitoring.

Isabelle Ligi1, Véronique Millet, Catherine Sartor, Elisabeth Jouve, Sophie Tardieu, Roland Sambuc, Umberto Simeoni.   

Abstract

OBJECTIVES: To assess the impact of continuous incident reporting and subsequent prevention strategies on the incidence of severe iatrogenic events and targeted priorities in admitted neonates.
METHODS: We performed preintervention (January 1 to September 1, 2005) and postintervention (January 1, 2008, to January 1, 2009) prospective investigations based on continuous incident reporting. Patient-safety initiatives were implemented for a period of 2 years. The main outcome was a reduction in the incidence of severe iatrogenic events. Secondary outcomes were improvements in 5 targeted priorities: catheter-related infections; invasive procedures; unplanned extubations; 10-fold drug infusion-rate errors; and severe cutaneous injuries.
RESULTS: The first and second study periods included totals of 388 and 645 patients (median gestational ages: 34 and 35 weeks, respectively; P = .015). In the second period the incidence of severe iatrogenic events was significantly reduced from 7.6 to 4.8 per 1000 patient-days (P = .005). Infections related to central catheters decreased significantly from 13.9 to 8.2 per 1000 catheter-days (P < .0001), as did exposure to central catheters, which decreased from 359 to 239 days per 1000 patient-days (P < .0001). Tenfold drug-dosing errors were reduced significantly (P = .022). However, the number of unplanned extubations increased significantly from 5.6 to 15.5 per 1000 ventilation-days (P = .03).
CONCLUSIONS: Prospective, continuous incident reporting followed by the implementation of prevention strategies are complementary procedures that constitute an effective system to improve the quality of care and patient safety.

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Year:  2010        PMID: 21078738     DOI: 10.1542/peds.2009-2872

Source DB:  PubMed          Journal:  Pediatrics        ISSN: 0031-4005            Impact factor:   7.124


  10 in total

1.  Incident reports versus direct observation to identify medication errors and risk factors in hospitalised newborns.

Authors:  David Palmero; Ermindo R Di Paolo; Corinne Stadelmann; André Pannatier; Farshid Sadeghipour; Jean-François Tolsa
Journal:  Eur J Pediatr       Date:  2018-11-21       Impact factor: 3.183

2.  Factors associated with iatrogenesis in neonatal intensive care units: an observational multicenter study.

Authors:  Einav Srulovici; Liora Ore; Eric S Shinwell; Shraga Blazer; Shmuel Zangen; Arieh Riskin; David Bader; Amir Kugelman
Journal:  Eur J Pediatr       Date:  2012-07-28       Impact factor: 3.183

Review 3.  Medication errors in pediatric emergencies: a systematic analysis.

Authors:  Jost Kaufmann; Michael Laschat; Frank Wappler
Journal:  Dtsch Arztebl Int       Date:  2012-09-21       Impact factor: 5.594

4.  Neurodevelopmental impairment in preterm infants with late-onset infection: not only in extremely preterm infants.

Authors:  Alexis Chenouard; Géraldine Gascoin; Christèle Gras-Le Guen; Yannis Montcho; Jean-Christophe Rozé; Cyril Flamant
Journal:  Eur J Pediatr       Date:  2014-02-27       Impact factor: 3.183

Review 5.  Interventions to reduce medication errors in neonatal care: a systematic review.

Authors:  Minh-Nha Rhylie Nguyen; Cassandra Mosel; Luke E Grzeskowiak
Journal:  Ther Adv Drug Saf       Date:  2017-12-28

6.  Valvular heart team.

Authors:  Max Grinberg
Journal:  Arq Bras Cardiol       Date:  2014-07       Impact factor: 2.000

7.  Incidence and mortality from adverse effects of medical treatment in the UK, 1990-2013: levels, trends, patterns and comparisons.

Authors:  Raimundas Lunevicius; Juanita A Haagsma
Journal:  Int J Qual Health Care       Date:  2018-08-01       Impact factor: 2.038

8.  Reducing Unplanned Extubations in a Level IV Neonatal Intensive Care Unit: The Elusive Benchmark.

Authors:  Maheshwar Mahaseth; Eunice Woldt; Mary Ellen Zajac; Brande Mazzeo; Jennie Basirico; Girija Natarajan
Journal:  Pediatr Qual Saf       Date:  2020-10-23

Review 9.  Less is More: Modern Neonatology.

Authors:  Amir Kugelman; Liron Borenstein-Levin; Huda Jubran; Gil Dinur; Shlomit Ben-David; Elena Segal; Julie Haddad; Fanny Timstut; Iris Stein; Imad R Makhoul; Ori Hochwald
Journal:  Rambam Maimonides Med J       Date:  2018-07-30

10.  Global Trends and Forecast of the Burden of Adverse Effects of Medical Treatment: Epidemiological Analysis Based on the Global Burden of Disease Study.

Authors:  Moien Ab Khan; Elpidoforos S Soteriades; Jeff King; Romona Govender; Muhammad Jawad Hashim; Shamaila Masood-Husain; Syed Fahad Javaid; Shaikha Debaib Mohammed Saeed Al Darei; Shamma Dahi Al Sheryani; Javaid Nauman
Journal:  Cureus       Date:  2020-03-12
  10 in total

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