J H Check1, R Cohen, D Check. 1. The University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School at Camden, Cooper Hospital/University Medical Center, Department of Obstetrics and Gynecology, Division of Reproductive Endocrinology & Infertility, Camden, NJ, USA. laurie@ccivf.com
Abstract
PURPOSE: To determine if the treatment of cold induced urticaria refractory to conventional antihistamine-type therapy would respond to treatment with sympathomimetic amines. METHODS: Dextroamphetamine sulfate (15 mg) extended release capsules were prescribed to be taken daily in the morning. RESULTS: The cold-induced urticaria completely disappeared and antihistamine therapy was discontinued. CONCLUSIONS: Treatment of chronic refractory cold-induced urticaria effectively responds to treatment with sympathomimetic amines similar to other cases of chronic refractory urticaria that are not merely cold induced. Manifestation of idiopathic orthostatic edema, a condition predominantly of women, should always be considered in the differential diagnosis of baffling medical conditions.
PURPOSE: To determine if the treatment of cold induced urticaria refractory to conventional antihistamine-type therapy would respond to treatment with sympathomimetic amines. METHODS:Dextroamphetamine sulfate (15 mg) extended release capsules were prescribed to be taken daily in the morning. RESULTS: The cold-induced urticaria completely disappeared and antihistamine therapy was discontinued. CONCLUSIONS: Treatment of chronic refractory cold-induced urticaria effectively responds to treatment with sympathomimetic amines similar to other cases of chronic refractory urticaria that are not merely cold induced. Manifestation of idiopathic orthostatic edema, a condition predominantly of women, should always be considered in the differential diagnosis of baffling medical conditions.