OBJECTIVE: To report a case of antenatally diagnosed congenital mesoblastic nephroma in an assisted reproductive technology (ART) conception. DESIGN: Case report. SETTING: Tertiary care university-affiliated hospital. PATIENT(S): Fetus of 26-weeks' gestation with antenatally diagnosed large abdominal tumor. INTERVENTION(S): ART with transfer of cryopreserved embryo. MAIN OUTCOME MEASURE(S): Postmortem examination. RESULT(S): Examination revealed a congenital mesoblastic nephroma, mixed classic and cellular type, with marked intratumoral hemorrhage and associated hydrops. The marked fetal erythroblastosis was suggestive of fetal response to pronounced anemia. Intrauterine demise is attributed to fetal intratumoral hemorrhage and early nonimmune hydrops secondary to a large congenital mesoblastic nephroma. CONCLUSION(S): This is the third reported case of congenital mesoblastic nephroma in an ART conception. Whether the association between mesoblastic nephroma and ART is coincidental or causative remains to be determined.
OBJECTIVE: To report a case of antenatally diagnosed congenital mesoblastic nephroma in an assisted reproductive technology (ART) conception. DESIGN: Case report. SETTING: Tertiary care university-affiliated hospital. PATIENT(S): Fetus of 26-weeks' gestation with antenatally diagnosed large abdominal tumor. INTERVENTION(S): ART with transfer of cryopreserved embryo. MAIN OUTCOME MEASURE(S): Postmortem examination. RESULT(S): Examination revealed a congenital mesoblastic nephroma, mixed classic and cellular type, with marked intratumoral hemorrhage and associated hydrops. The marked fetal erythroblastosis was suggestive of fetal response to pronounced anemia. Intrauterine demise is attributed to fetal intratumoral hemorrhage and early nonimmune hydrops secondary to a large congenital mesoblastic nephroma. CONCLUSION(S): This is the third reported case of congenital mesoblastic nephroma in an ART conception. Whether the association between mesoblastic nephroma and ART is coincidental or causative remains to be determined.