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Literature DB >> 21075227

An odyssey of fear: Homer stresses new mechanisms.

Sachin Patel¹, Danny G Winder.

Abstract

Entities: Chemical Disease Gene

Mesh：

Substances：

Year: 2010 PMID： 21075227 PMCID： PMC3035943 DOI： 10.1016/j.biopsych.2010.10.005

Source DB: PubMed Journal: Biol Psychiatry ISSN： 0006-3223 Impact factor: 13.382

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10 in total

1. Agonist-independent activation of metabotropic glutamate receptors by the intracellular protein Homer.

Authors: F Ango; L Prézeau; T Muller; J C Tu; B Xiao; P F Worley; J P Pin; J Bockaert; L Fagni
Journal: Nature Date: 2001-06-21 Impact factor: 49.962

2. Prevalence of mental health problems and functional impairment among active component and National Guard soldiers 3 and 12 months following combat in Iraq.

Authors: Jeffrey L Thomas; Joshua E Wilk; Lyndon A Riviere; Dennis McGurk; Carl A Castro; Charles W Hoge
Journal: Arch Gen Psychiatry Date: 2010-06

3. Metabotropic glutamate receptor 5/Homer interactions underlie stress effects on fear.

Authors: Natalie C Tronson; Yomayra F Guzman; Anita L Guedea; Kyu Hwan Huh; Can Gao; Martin K Schwarz; Jelena Radulovic
Journal: Biol Psychiatry Date: 2010-12-01 Impact factor: 13.382

4. Modulation of learning and anxiety by corticotropin-releasing factor (CRF) and stress: differential roles of CRF receptors 1 and 2.

Authors: J Radulovic; A Rühmann; T Liepold; J Spiess
Journal: J Neurosci Date: 1999-06-15 Impact factor: 6.167

An odyssey of fear: Homer stresses new mechanisms.

1. Agonist-independent activation of metabotropic glutamate receptors by the intracellular protein Homer.

2. Prevalence of mental health problems and functional impairment among active component and National Guard soldiers 3 and 12 months following combat in Iraq.

3. Metabotropic glutamate receptor 5/Homer interactions underlie stress effects on fear.

4. Modulation of learning and anxiety by corticotropin-releasing factor (CRF) and stress: differential roles of CRF receptors 1 and 2.

Review 5. Potential psychiatric applications of metabotropic glutamate receptor agonists and antagonists.

Review 6. Critical brain circuits at the intersection between stress and learning.

Review 7. Metabotropic glutamate receptors: physiology, pharmacology, and disease.

8. Tailoring therapeutic strategies for treating posttraumatic stress disorder symptom clusters.

9. mGluR5 has a critical role in inhibitory learning.

Review 10. How the neurocircuitry and genetics of fear inhibition may inform our understanding of PTSD.