| Literature DB >> 21074426 |
Gillian E Lunniss1, Ashley A Barnes, Nick Barton, Matteo Biagetti, Federica Bianchi, Stephen M Blowers, Laura L Caberlotto, Amanda Emmons, Ian P Holmes, Dino Montanari, Roz Norris, Gemma V Puckey, Dewi J Walters, Steve P Watson, John Willis.
Abstract
The identification and subsequent optimisation of a selective non-peptidic NPY Y2 antagonist series is described. This led to the development of amine 2, a selective, soluble NPY Y2 receptor antagonist with enhanced CNS exposure.Entities:
Mesh：
Substances：
Year: 2010 PMID： 21074426 DOI： 10.1016/j.bmcl.2010.10.065
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823