Literature DB >> 21072384

Selective mitochondrial accumulation of cytotoxic dinuclear polypyridyl ruthenium(II) complexes.

Michelle J Pisani1, Daniel K Weber, Kirsten Heimann, J Grant Collins, F Richard Keene.   

Abstract

The lipophilic ligand-bridged dinuclear cation Rubb₁₆ is significantly cytotoxic and preferentially accumulates in the mitochondria of the L1210 murine leukemia cancer cell line.

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Year:  2010        PMID： 21072384     DOI： 10.1039/c004922k

Source DB:  PubMed          Journal:  Metallomics        ISSN： 1756-5901            Impact factor:   4.526


  8 in total

1.  DNA molecular recognition and cellular selectivity of anticancer metal(II) complexes of ethylenediaminediacetate and phenanthroline: multiple targets.

Authors:  Sze-Tin Von; Hoi-Ling Seng; Hong-Boon Lee; Seik-Weng Ng; Yusuke Kitamura; Makoto Chikira; Chew-Hee Ng
Journal:  J Biol Inorg Chem       Date:  2011-08-11       Impact factor: 3.358

2.  Effects of chirality on the intracellular localization of binuclear ruthenium(II) polypyridyl complexes.

Authors:  Frida R Svensson; Johanna Andersson; Helene L Åmand; Per Lincoln
Journal:  J Biol Inorg Chem       Date:  2012-02-05       Impact factor: 3.358

3.  Mitochondria are the primary target in the induction of apoptosis by chiral ruthenium(II) polypyridyl complexes in cancer cells.

Authors:  Jin-Quan Wang; Ping-Yu Zhang; Chen Qian; Xiao-Juan Hou; Liang-Nian Ji; Hui Chao
Journal:  J Biol Inorg Chem       Date:  2013-11-28       Impact factor: 3.358

4.  Regression of lung cancer by hypoxia-sensitizing ruthenium polypyridyl complexes.

Authors:  Abhishek Yadav; Thamara Janaratne; Arthi Krishnan; Sharad S Singhal; Sushma Yadav; Adam S Dayoub; Doyle L Hawkins; Sanjay Awasthi; Frederick M MacDonnell
Journal:  Mol Cancer Ther       Date:  2013-02-26       Impact factor: 6.261

5.  A ruthenium dimer complex with a flexible linker slowly threads between DNA bases in two distinct steps.

Authors:  Meriem Bahira; Micah J McCauley; Ali A Almaqwashi; Per Lincoln; Fredrik Westerlund; Ioulia Rouzina; Mark C Williams
Journal:  Nucleic Acids Res       Date:  2015-09-13       Impact factor: 16.971

6.  Precision targeted ruthenium(ii) luminophores; highly effective probes for cell imaging by stimulated emission depletion (STED) microscopy.

Authors:  Aisling Byrne; Christopher S Burke; Tia E Keyes
Journal:  Chem Sci       Date:  2016-06-30       Impact factor: 9.825

7.  Cellular and cell-free studies of catalytic DNA cleavage by ruthenium polypyridyl complexes containing redox-active intercalating ligands.

Authors:  Cynthia Griffith; Adam S Dayoub; Thamara Jaranatne; Nagham Alatrash; Ali Mohamedi; Kenneth Abayan; Zachary S Breitbach; Daniel W Armstrong; Frederick M MacDonnell
Journal:  Chem Sci       Date:  2017-03-08       Impact factor: 9.825

Review 8.  Ruthenium Complexes in the Fight against Pathogenic Microorganisms. An Extensive Review.

Authors:  Alexandra-Cristina Munteanu; Valentina Uivarosi
Journal:  Pharmaceutics       Date:  2021-06-13       Impact factor: 6.321
  8 in total

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