Literature DB >> 21070532

Treatment of tendinopathy: is there a role for autologous whole blood and platelet rich plasma injection?

R J Kampa1, D A Connell.   

Abstract

BACKGROUND: Chronic tendinopathies are a common source of disability and can be recalcitrant to conservative measures, which once exhausted may necessitate operative intervention. Blood and platelets, in particular, are a rich source of factors necessary for tissue healing. Autologous blood injections (ABI) are thought to promote tendon healing, but have been explored clinically in only a few limited studies. However, recently they have attracted media attention in relation to the world of professional athletes and sports-related injuries.
METHOD: We review the evidence base for this technique using the available literature on PubMed.
CONCLUSION: Refractory chronic tendinopathy may be responsive to ABIs, but the data available to date are limited by quality and size of study, as well as length of follow up, and are currently insufficient to recommend this modality for routine clinical use.
© 2010 Blackwell Publishing Ltd.

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Year:  2010        PMID: 21070532     DOI: 10.1111/j.1742-1241.2010.02432.x

Source DB:  PubMed          Journal:  Int J Clin Pract        ISSN: 1368-5031            Impact factor:   2.503


  16 in total

1.  Optimized Repopulation of Tendon Hydrogel: Synergistic Effects of Growth Factor Combinations and Adipose-Derived Stem Cells.

Authors:  Simon Farnebo; Lovisa Farnebo; Maxwell Kim; Colin Woon; Hung Pham; James Chang
Journal:  Hand (N Y)       Date:  2016-03-15

Review 2.  Augmenting tendon and ligament repair with platelet-rich plasma (PRP).

Authors:  Ting Yuan; Chang-Qing Zhang; James H-C Wang
Journal:  Muscles Ligaments Tendons J       Date:  2013-08-11

3.  Efficacy of intra-tendinous injection of platelet-rich plasma in treating tendinosis: comprehensive assessment of a rat model.

Authors:  Benjamin Dallaudière; Marta Lempicki; Lionel Pesquer; Liliane Louedec; Pierre Marie Preux; Philippe Meyer; Vincent Hummel; Ahmed Larbi; Lydia Deschamps; Clement Journe; Agathe Hess; Alain Silvestre; Paul Sargos; Philippe Loriaut; Patrick Boyer; Elisabeth Schouman-Claeys; Jean Baptiste Michel; Jean Michel Serfaty
Journal:  Eur Radiol       Date:  2013-06-26       Impact factor: 5.315

Review 4.  Anaesthetics, steroids and platelet-rich plasma (PRP) in ultrasound-guided musculoskeletal procedures.

Authors:  Antonio Barile; Alice La Marra; Francesco Arrigoni; Silvia Mariani; Luigi Zugaro; Alessandra Splendiani; Ernesto Di Cesare; Alfonso Reginelli; Marcello Zappia; Luca Brunese; Ejona Duka; Giampaolo Carrafiello; Carlo Masciocchi
Journal:  Br J Radiol       Date:  2016-07-07       Impact factor: 3.039

5.  Conservative management of Achilles Tendinopathy: a case report.

Authors:  John A Papa
Journal:  J Can Chiropr Assoc       Date:  2012-09

Review 6.  Autologous blood and platelet-rich plasma injection therapy for lateral elbow pain.

Authors:  Teemu V Karjalainen; Michael Silagy; Edward O'Bryan; Renea V Johnston; Sheila Cyril; Rachelle Buchbinder
Journal:  Cochrane Database Syst Rev       Date:  2021-09-30

7.  Combined intra-tendinous injection of Platelet Rich Plasma and bevacizumab accelerates and improves healing compared to Platelet Rich Plasma in tendinosis: comprehensive assessment on a rat model.

Authors:  Benjamin Dallaudiere; Olivier Zurlinden; Anne Perozziello; Lydia Deschamps; Ahmed Larbi; Liliane Louedec; Lionel Pesquer; Yohan Benayoun; Alain Silvestre; Jean Michel Serfaty
Journal:  Muscles Ligaments Tendons J       Date:  2014-11-17

8.  Is Platelet-rich Plasma Injection Effective for Chronic Achilles Tendinopathy? A Meta-analysis.

Authors:  Yi-Jun Zhang; San-Zhong Xu; Peng-Cheng Gu; Jing-Yu Du; You-Zhi Cai; Chi Zhang; Xiang-Jin Lin
Journal:  Clin Orthop Relat Res       Date:  2018-08       Impact factor: 4.176

9.  Plantar fasciitis.

Authors:  Mohammad Ali Tahririan; Mehdi Motififard; Mohammad Naghi Tahmasebi; Babak Siavashi
Journal:  J Res Med Sci       Date:  2012-08       Impact factor: 1.852

10.  Tendinopathy in sport.

Authors:  Paul W Ackermann; Per Renström
Journal:  Sports Health       Date:  2012-05       Impact factor: 3.843

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