| Literature DB >> 21068292 |
Marco Artini1, Carlo Romanò, Lamberto Manzoli, Gian Luca Scoarughi, Rosanna Papa, Enzo Meani, Lorenzo Drago, Laura Selan.
Abstract
Delayed orthopedic joint prosthesis infections (DOJP-Is) due to staphylococci frequently result in prosthetic revision. Specific and noninvasive diagnostic tests are unavailable, and DOJP-Is are commonly diagnosed at advanced stages of disease. An enzyme-linked immunosorbent assay (ELISA) was developed to detect serum antibodies against staphylococcal slime polysaccharide antigens. Using a cutoff of 0.35 ELISA units, the test showed a specificity of 95.1% (95% confidence interval [CI], 85.4 to 98.7%) and a sensitivity of 89.7% (71.5 to 97.3%) on a sample of 90 individuals.Entities:
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Year: 2010 PMID: 21068292 PMCID: PMC3020415 DOI: 10.1128/JCM.01836-10
Source DB: PubMed Journal: J Clin Microbiol ISSN: 0095-1137 Impact factor: 5.948