Literature DB >> 21068054

Conditional decomposition diagnostics for regression analysis of zero-inflated and left-censored data.

Yan Yang1, Douglas G Simpson.   

Abstract

Health and safety studies that entail both incidence and magnitude of effects produce semi-continuous outcomes, in which the response is either zero or a continuous positive value. Zero-inflated left-censored models typically employ latent mixture constructions to allow different covariate processes to impact the incidence versus the magnitude. Assessment of the model, however, requires a focus on the observable characteristics. We employ a conditional decomposition approach, in which the model assessment is partitioned into two observable components: the adequacy of the marginal probability model for the boundary value and the adequacy of the conditional model for values strictly above the boundary. A conditional likelihood decomposition facilitates the statistical assessment. For corresponding residual and graphical analysis, the conditional mean and quantile functions for events above the boundary and the marginal probabilities of boundary events are investigated. Large sample standard errors for these quantities are derived for enhanced graphical assessment, and simulation is conducted to investigate the finite-sample behaviour. The methods are illustrated with data from two health-related safety studies. In each case, the conditional assessments identify the source for lack of fit of the previously considered model and thus lead to an improved model.

Entities:  

Mesh:

Year:  2010        PMID: 21068054      PMCID: PMC3949496          DOI: 10.1177/0962280210387525

Source DB:  PubMed          Journal:  Stat Methods Med Res        ISSN: 0962-2802            Impact factor:   3.021


  18 in total

1.  A mixture model for occupational exposure mean testing with a limit of detection.

Authors:  D J Taylor; L L Kupper; S M Rappaport; R H Lyles
Journal:  Biometrics       Date:  2001-09       Impact factor: 2.571

2.  Comparison of several independent population means when their samples contain log-normal and possibly zero observations.

Authors:  X H Zho; W Tu
Journal:  Biometrics       Date:  1999-06       Impact factor: 2.571

3.  Excess risk thresholds in ultrasound safety studies: statistical methods for data on occurrence and size of lesions.

Authors:  Douglas G Simpson; Moon-Ho Ho; Yan Yang; Jianhui Zhou; James F Zachary; William D O'Brien
Journal:  Ultrasound Med Biol       Date:  2004-10       Impact factor: 2.998

4.  Smooth tests for the zero-inflated poisson distribution.

Authors:  Olivier Thas; J C W Rayner
Journal:  Biometrics       Date:  2005-09       Impact factor: 2.571

5.  Assessing influence for pharmaceutical data in zero-inflated generalized Poisson mixed models.

Authors:  Feng-Chang Xie; Bo-Cheng Wei; Jin-Guan Lin
Journal:  Stat Med       Date:  2008-08-15       Impact factor: 2.373

6.  The zero-inflated negative binomial regression model with correction for misclassification: an example in caries research.

Authors:  Samuel M Mwalili; Emmanuel Lesaffre; Dominique Declerck
Journal:  Stat Methods Med Res       Date:  2007-08-14       Impact factor: 3.021

7.  A hierarchical zero-inflated log-normal model for skewed responses.

Authors:  David A Elashoff; Wendie A Robbins
Journal:  Stat Methods Med Res       Date:  2008-09-24       Impact factor: 3.021

8.  A mixed gamma model for regression analyses of quantitative assay data.

Authors:  L H Moulton; N A Halsey
Journal:  Vaccine       Date:  1996-08       Impact factor: 3.641

9.  Zero inflation in ordinal data: incorporating susceptibility to response through the use of a mixture model.

Authors:  Mary E Kelley; Stewart J Anderson
Journal:  Stat Med       Date:  2008-08-15       Impact factor: 2.373

10.  Use of log-skew-normal distribution in analysis of continuous data with a discrete component at zero.

Authors:  High Seng Chai; Kent R Bailey
Journal:  Stat Med       Date:  2008-08-15       Impact factor: 2.373

View more
  1 in total

Review 1.  A Review on Differential Abundance Analysis Methods for Mass Spectrometry-Based Metabolomic Data.

Authors:  Zhengyan Huang; Chi Wang
Journal:  Metabolites       Date:  2022-03-30
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.