Literature DB >> 21063816

Application of in situ polymerization for design and development of oral drug delivery systems.

Ndidi Ngwuluka1.   

Abstract

Although preformed polymers are commercially available for use in the design and development of drug delivery systems, in situ polymerization has also been employed. In situ polymerization affords the platform to tailor and optimize the drug delivery properties of polymers. This review brings to light the benefits of in situ polymerization for oral drug delivery and the possibilities it provides to overcome the challenges of oral route of administration.

Entities:  

Mesh：

Substances：

Year:  2010        PMID： 21063816      PMCID： PMC3011060          DOI： 10.1208/s12249-010-9535-4

Source DB:  PubMed          Journal:  AAPS PharmSciTech        ISSN： 1530-9932            Impact factor:   3.246


  37 in total

1.  Release performance of a poorly soluble drug from a novel, Eudragit-based multi-unit erosion matrix.

Authors:  K A Mehta; M S Kislalioglu; W Phuapradit; A W Malick; N H Shah
Journal:  Int J Pharm       Date:  2001-02-01       Impact factor: 5.875

2.  Using different structure types of microemulsions for the preparation of poly(alkylcyanoacrylate) nanoparticles by interfacial polymerization.

Authors:  K Krauel; N M Davies; S Hook; T Rades
Journal:  J Control Release       Date:  2005-08-18       Impact factor: 9.776

3.  Nanoparticles containing ketoprofen and acrylic polymers prepared by an aerosol flow reactor method.

Authors:  Hannele Eerikäinen; Leena Peltonen; Janne Raula; Jouni Hirvonen; Esko I Kauppinen
Journal:  AAPS PharmSciTech       Date:  2004-09-23       Impact factor: 3.246

4.  Sustained release pellets based on poly(N-isopropyl acrylamide): matrix and in situ photopolymerization-coated systems.

Authors:  Marcos Mayo-Pedrosa; Carmen Alvarez-Lorenzo; Igor Lacík; Ramon Martinez-Pacheco; Angel Concheiro
Journal:  J Pharm Sci       Date:  2007-01       Impact factor: 3.534

5.  Preparation of biodegradable insulin nanocapsules from biocompatible microemulsions.

Authors:  S Watnasirichaikul; N M Davies; T Rades; I G Tucker
Journal:  Pharm Res       Date:  2000-06       Impact factor: 4.200

6.  Elucidation of the mechanism of incorporation of insulin in controlled release systems based on complexation polymers.

Authors:  Mariko Morishita; Anthony M Lowman; Kozo Takayama; Tsuneji Nagai; Nicholas A Peppas
Journal:  J Control Release       Date:  2002-05-17       Impact factor: 9.776

7.  Chitosan capsules for colon-specific drug delivery: enhanced localization of 5-aminosalicylic acid in the large intestine accelerates healing of TNBS-induced colitis in rats.

Authors:  Hideyuki Tozaki; Tomokazu Odoriba; Naoki Okada; Takuya Fujita; Akira Terabe; Tsutomu Suzuki; Susumu Okabe; Shozo Muranishi; Akira Yamamoto
Journal:  J Control Release       Date:  2002-07-18       Impact factor: 9.776

Review 8.  Alginate in drug delivery systems.

Authors:  Hanne Hjorth Tønnesen; Jan Karlsen
Journal:  Drug Dev Ind Pharm       Date:  2002-07       Impact factor: 3.225

9.  Poly(fumaric-co-sebacic) microspheres as oral drug delivery systems.

Authors:  D Chickering; J Jacob; E Mathiowitz
Journal:  Biotechnol Bioeng       Date:  1996-10-05       Impact factor: 4.530

10.  pH-Sensitive hydrogels as gastrointestinal tract absorption enhancers: transport mechanisms of salmon calcitonin and other model molecules using the Caco-2 cell model.

Authors:  Madeline Torres-Lugo; Marcos García; Rae Record; Nicholas A Peppas
Journal:  Biotechnol Prog       Date:  2002 May-Jun
View more
  2 in total

1.  Vancomycin-loaded HPMC microparticles embedded within injectable thermosensitive chitosan hydrogels.

Authors:  M Mahmoudian; F Ganji
Journal:  Prog Biomater       Date:  2017-04-26

Review 2.  Stimuli-Responsive Materials for Tissue Engineering and Drug Delivery.

Authors:  Sofia Municoy; María I Álvarez Echazú; Pablo E Antezana; Juan M Galdopórpora; Christian Olivetti; Andrea M Mebert; María L Foglia; María V Tuttolomondo; Gisela S Alvarez; John G Hardy; Martin F Desimone
Journal:  Int J Mol Sci       Date:  2020-07-02       Impact factor: 5.923
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.