Literature DB >> 21062081

Histamine H3 receptor as a drug discovery target.

Michael Berlin1, Christopher W Boyce, Manuel de Lera Ruiz.   

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Year:  2010        PMID： 21062081     DOI： 10.1021/jm100064d

Source DB:  PubMed          Journal:  J Med Chem        ISSN： 0022-2623            Impact factor:   7.446


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  28 in total

1.  Radiosynthesis and evaluation of an (18)F-labeled positron emission tomography (PET) radioligand for brain histamine subtype-3 receptors based on a nonimidazole 2-aminoethylbenzofuran chemotype.

Authors:  Xiaofeng Bao; Shuiyu Lu; Jeih-San Liow; Sami S Zoghbi; Kimberly J Jenko; David T Clark; Robert L Gladding; Robert B Innis; Victor W Pike
Journal:  J Med Chem       Date:  2012-02-16       Impact factor: 7.446

2.  Heterologous, PKC-Mediated Desensitization of Human Histamine H3 Receptors Expressed in CHO-K1 Cells.

Authors:  Wilber Montejo-López; Nayeli Rivera-Ramírez; Juan Escamilla-Sánchez; Ubaldo García-Hernández; José-Antonio Arias-Montaño
Journal:  Neurochem Res       Date:  2016-06-27       Impact factor: 3.996

3.  Central nervous system effects of the histamine-3 receptor antagonist CEP-26401, in comparison with modafinil and donepezil, after a single dose in a cross-over study in healthy volunteers.

Authors:  Anne C Baakman; Rob Zuiker; Joop M A van Gerven; Nicholas Gross; Ronghua Yang; Michael Fetell; Ari Gershon; Yossi Gilgun-Sherki; Edward Hellriegel; Ofer Spiegelstein
Journal:  Br J Clin Pharmacol       Date:  2019-03-14       Impact factor: 4.335

4.  The Concise Guide to PHARMACOLOGY 2013/14: G protein-coupled receptors.

Authors:  Stephen P H Alexander; Helen E Benson; Elena Faccenda; Adam J Pawson; Joanna L Sharman; Michael Spedding; John A Peters; Anthony J Harmar
Journal:  Br J Pharmacol       Date:  2013-12       Impact factor: 8.739

Review 5.  Multiple Targeting Approaches on Histamine H3 Receptor Antagonists.

Authors:  Mohammad A Khanfar; Anna Affini; Kiril Lutsenko; Katarina Nikolic; Stefania Butini; Holger Stark
Journal:  Front Neurosci       Date:  2016-05-30       Impact factor: 4.677

6.  Structure-based prediction of subtype selectivity of histamine H3 receptor selective antagonists in clinical trials.

Authors:  Soo-Kyung Kim; Peter Fristrup; Ravinder Abrol; William A Goddard
Journal:  J Chem Inf Model       Date:  2011-11-16       Impact factor: 4.956

7.  Discovery of a potent thiadiazole class of histamine h3 receptor antagonist for the treatment of diabetes.

Authors:  Ashwin U Rao; Ning Shao; Robert G Aslanian; Tin-Yau Chan; Sylvia J Degrado; Li Wang; Brian McKittrick; Mary Senior; Robert E West; Shirley M Williams; Ren-Long Wu; Joyce Hwa; Bhuneshwari Patel; Shuqin Zheng; Christopher Sondey; Anandan Palani
Journal:  ACS Med Chem Lett       Date:  2011-11-21       Impact factor: 4.345

8.  Histamine induces chemotaxis and phagocytosis in murine bone marrow-derived macrophages and RAW 264.7 macrophage-like cells via histamine H4-receptor.

Authors:  Christoph P Czerner; Andreas Klos; Roland Seifert; Detlef Neumann
Journal:  Inflamm Res       Date:  2013-12-08       Impact factor: 4.575

Review 9.  International Union of Basic and Clinical Pharmacology. XCVIII. Histamine Receptors.

Authors:  Pertti Panula; Paul L Chazot; Marlon Cowart; Ralf Gutzmer; Rob Leurs; Wai L S Liu; Holger Stark; Robin L Thurmond; Helmut L Haas
Journal:  Pharmacol Rev       Date:  2015-07       Impact factor: 25.468

10.  Synthesis, biological evaluation, and computational studies of Tri- and tetracyclic nitrogen-bridgehead compounds as potent dual-acting AChE inhibitors and hH3 receptor antagonists.

Authors:  Fouad H Darras; Steffen Pockes; Guozheng Huang; Sarah Wehle; Andrea Strasser; Hans-Joachim Wittmann; Martin Nimczick; Christoph A Sotriffer; Michael Decker
Journal:  ACS Chem Neurosci       Date:  2014-01-14       Impact factor: 4.418
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