OBJECTIVE: To address whether secretion removal techniques increase airway clearance in people with chronic spinal cord injury (SCI). DATA SOURCES AND STUDY SELECTION: MEDLINE/PubMed, CINAHL, EMBASE, and PsycINFO were searched from inception to May 2009 for population keywords (spinal cord injury, paraplegia, tetraplegia, quadriplegia) paired with secretion removal-related interventions and outcomes. Inclusion criteria for articles were a research study, irrespective of design, that examined secretion removal in people with chronic SCI published in English. REVIEW METHODS: Two reviewers determined whether articles met the inclusion criteria, abstracted information, and performed a quality assessment using PEDro or Downs and Black criteria. Studies were then given a level of evidence based on a modified Sackett scale. RESULTS: Of 2416 abstracts and titles retrieved, 24 met the inclusion criteria. Subjects were young (mean, 31 years) and 84% were male. Most evidence was level 4 or 5 and only 2 studies were randomized controlled trials. Three reports described outcomes for secretion removal techniques in addition to cough, whereas most articles examined the immediate effects of various components of cough. Studies examining insufflation combined with manual assisted cough provided the most consistent, high-level evidence. Compelling recent evidence supports the use of respiratory muscle training or electrical stimulation of the expiratory muscles to facilitate airway clearance in people with SCI. CONCLUSION: Evidence supporting the use of secretion removal techniques in SCI, while positive, is limited and mostly of low level. Treatments that increase respiratory muscle force show promise as effective airway clearance techniques.
OBJECTIVE: To address whether secretion removal techniques increase airway clearance in people with chronic spinal cord injury (SCI). DATA SOURCES AND STUDY SELECTION: MEDLINE/PubMed, CINAHL, EMBASE, and PsycINFO were searched from inception to May 2009 for population keywords (spinal cord injury, paraplegia, tetraplegia, quadriplegia) paired with secretion removal-related interventions and outcomes. Inclusion criteria for articles were a research study, irrespective of design, that examined secretion removal in people with chronic SCI published in English. REVIEW METHODS: Two reviewers determined whether articles met the inclusion criteria, abstracted information, and performed a quality assessment using PEDro or Downs and Black criteria. Studies were then given a level of evidence based on a modified Sackett scale. RESULTS: Of 2416 abstracts and titles retrieved, 24 met the inclusion criteria. Subjects were young (mean, 31 years) and 84% were male. Most evidence was level 4 or 5 and only 2 studies were randomized controlled trials. Three reports described outcomes for secretion removal techniques in addition to cough, whereas most articles examined the immediate effects of various components of cough. Studies examining insufflation combined with manual assisted cough provided the most consistent, high-level evidence. Compelling recent evidence supports the use of respiratory muscle training or electrical stimulation of the expiratory muscles to facilitate airway clearance in people with SCI. CONCLUSION: Evidence supporting the use of secretion removal techniques in SCI, while positive, is limited and mostly of low level. Treatments that increase respiratory muscle force show promise as effective airway clearance techniques.
Authors: Anthony F DiMarco; Raymond P Onders; Krzysztof E Kowalski; Michael E Miller; Sandra Ferek; J Thomas Mortimer Journal: Am J Respir Crit Care Med Date: 2002-12-15 Impact factor: 21.405
Authors: Ann M Spungen; David R Grimm; Gregory Schilero; Roberta Lenner; Erwin Oei; William A Bauman; Peter L Almenoff; Marvin Lesser Journal: J Spinal Cord Med Date: 2002 Impact factor: 1.985
Authors: Nicole L Nichols; J Van Dyke; L Nashold; I Satriotomo; M Suzuki; G S Mitchell Journal: Respir Physiol Neurobiol Date: 2013-05-18 Impact factor: 1.931