| Literature DB >> 21061224 |
Yan-Fang Yang1, Shi-Jin Qu, Kai Xiao, Shan-Hao Jiang, Jun-Jie Tan, Chang-Heng Tan, Da-Yuan Zhu.
Abstract
A new lycopodane-type Lycopodium alkaloid, 6α-hydroxy-5,15-oxide-lycopodane (1), and seven known alkaloids were isolated from the whole plants of Huperzia serrata. Their structures were elucidated by means of spectroscopic methods. 12-Deoxyhuperzine O (2) was reported as a naturally occurring alkaloid for the first time, and showed an antagonist effect on the N-methyl-d-aspartate receptor with an IC(50) value of 0.92 μM.Entities:
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Year: 2010 PMID： 21061224 DOI： 10.1080/10286020.2010.522180
Source DB: PubMed Journal: J Asian Nat Prod Res ISSN： 1028-6020 Impact factor: 1.569